Wednesday, April 18, 2018

Gout Flare Pain

Gout Flare Pain

Also called “gouty arthritis,” gout is a painful form of arthritis caused by too much uric acid in the body.   The painful flare-ups may be concentrated in the big toe (a symptom known as podagra), as well as swelling and pain in the ankles, knees, feet, wrists or elbows. Flare-ups last days in the beginning, but can become progressively longer. Left untreated, gout can cause permanent damage to joints and kidneys, according to the National Institutes of Health (NIH).   Gout is most commonly seen in men, particularly those between the ages of 40 and 50. It is a very common disease. Six million adults age 20 and older have reported being diagnosed with gout according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

GOUT DIET AND GOUT SAFE FOOD- WHAT IS WRONG AND WHAT IS RIGHT?







Why do low-purine Gout diets alone fail to resolve Gout?


Is a healthy diet important to gout control? ABSOLUTELY! However, focusing solely on purines can lead to trouble. Only 30% of uric acid production stems directly from the purines in foods. The other 70% is manufactured from the dying cells in our body. Cells die at a much higher rate in the presence of unhealthy and unbalanced diets, stress, medications, environmental toxins, weight problems, and our overall lifestyle.

We cannot fully control all of the toxins and acids in our environment that contribute to our cellular degeneration. Perfect diets can be quite challenging, if not impossible. We MUST approach gout healing and continued gout control with a fully comprehensive plan including diet, lifestyle, vitamins, and supplement(s) to provide the best support system possible.

Purines are found in every plant and animal cells. Purines include adenine, guanine, hypoxanthine, and xanthine. Purines constitute one of the major parts of our genetic codes, DNA and RNA, and energy molecules such as ATP, GTP and coenzyme A. Purine molecules are essential to all of life.


Meat (100 g / 3.5 oz)
Purine
Uric Acid

Mutton Chop

61

146
Mutton Saddle
81
195
Veal, lean
63
150
Sweetbreads
525
1260
Veal Chop
52
125
Veal Liver
182
460
Veal Kidney
88
210
Lamb, lean
76
182
Horse Meat
83
200
Beef Heart
107
256
Bovine Liver
231
554
Bovine Lung
166
399
Bovine Kidney
112
269
Beef Tongue
67
160
Beef, lean
58
140
Pork, lean
63
150
Pork Liver
125
300
Pork Kidney
139
334
Pork Shoulder, raw
63
150
Pork Shoulder, roast
83
200
Pork Shoulder, skin
116
280
Pork Chops
49
118
Roast Hare
71
170
Venison
67
160
Rabbit
60
145


Sausage and Ham (100 g / 3.5 oz)
Purine
Uric Acid

Black Pudding

38

90
Bratwurst
54
130
Meat Extract
1459
3500
Meat Loaf
58
130
Frankfurter Sausages
54
130
Mortadella
54
130
Ham, cooked
83
198
Ham, smoked
84
200


Fish (100 g / 3.5 oz)
Purine
Uric Acid
Trout
83
200
Pike
58
140
Halibut
123
294
Herring
79
194
Herring Fillet
88
210
Herring Roe
79
190
Cod
63
150
Carp
63
150
Salmon
68
163
Mackerel
60
145
Mackerel, raw, with skin
167
400
Mackerel, raw, without skin
75
180
Redfish
100
241
Sardine
144
345
Haddock
54
130
Plaice
58
140
Plaice, raw, with skin
71
170
Plaice, raw, without skin
54
130
Sole
55
131
Tuna
107
257
Pike
46
110


Poultry (100 g / 3.5 oz)
Purine
Uric Acid
Duck
64
153
Pheasant
62
150
Goose
69
165
Chicken Leg, roasted
98
235
Chicken with Skin, roasted
125
300
Turkey
50
120
Chicken Liver
101
243



Mushrooms (100 g / 3.5 oz)
Purine
Uric Acid
Portabella Mushrooms
25
60
Chanterelles
13
30
Porcini
34
80

Fish Products (100 g / 3.5 oz)
Purine
Uric Acid

Eel, smoked

48

115
Anchovies
108
260
Herring with skin, fried
88
210
Herring without skin, fried
67
160
Bow with skin
100
240
Bow without skin
60
145
Caviar
60
145
Salmon, smoked
100
242
Mackerel, smoked
76
182
Herring
91
219
Sardines with skin
146
350
Sardines without skin
88
210
Sardines in oil
200
480
Sprat, smoked
223
535
Tuna in oil
121
290


Shellfish and Crustaceans (100 g / 3.5 oz)
Purine
Uric Acid

Oyster

38

90
Shrimp
61
147
Lobster
73
175
Cancer
25
60
Mussel
154
370





Fruit (100 g / 3.5 oz)
Purine
Uric Acid

Pineapple

8

20
Apple
6
15
Apricot
8
20
Apricot, dried
32
75
Banana
11
25
Pear
6
15


Blackberries
5
15
Date
21
50
Strawberries
11
25
Banana
11
25
Blueberries
8
20
Raspberries
8
18
Cherry
6
15
Orange
8
20
Peach
8
18
Cranberries
5
13
Watermelon
8
20
Grape, blue
8
20
Grapes, white
8
20
Plum
8
20




Drinks with and without Alcohol (100 g / 3.5 oz)
Purine
Uric Acid

Apple Juice

3

8
Beer
27
65
Beer Yeast
1248
2995
Beer without alcohol
1
3
Coffee
0
0
Orange Juice
5
12
Champagne
0
0
Spirits
0
0
Tea
0
0
Wine
0
0
 
Legumes and Soybeans (100 g / 3.5 oz)
Purine
Uric Acid

Beans, white

75

180
Peas
62
150
Peek
84
200
Soybeans
92
220
Soybean Flour
123
296
Tofu
29
70
Soy Sauce
25
60

Cereals, Rice, Noodles (100 g / 3.5 oz)
Purine
Uric Acid

Buckwheat

62

149
Barley
34
82
Semolina
23
55
Oatmeal
42
100
Millet
35
85
Rice, unprocessed, cooked)
15
35
Rice, white, cooked
10
25
Rye, whole grain
20
47
Sago
34
82
Starch
0
0
Tapioca
37
89
Whole Grain Bread
35
84
Wheat, whole grain
17
40
Wheat Flour
8
20
Noodles, cooked
22
52
Whole Wheat Pasta, cooked
21
50


Nuts and Seeds (100 g / 3.5 oz)
Purine
Uric Acid

Peanuts

42

100
Hazelnuts
13
30
Almonds
13
30
Pecans
13
30
Poppy
70
154
Sesame Seeds
37
88
Sunflower Seeds
65
157
Walnuts
10
25


Vegetables (100 g / 3.5 oz)
Purine
Uric Acid

Eggplant

8

20
Bamboo Shoots
6
15
Cauliflower
19
45
Beans, green
18
42
Avocado
13
30
Broccoli
21
50
Chicory
6
15
Chinese Cabbage
10
25
Endive
4
11
Lamb's lettuce
10
24
Fennel
7
16
Kale
13
30
Carrot
6
15
Potato
6
15
Kohlrabi
13
30
Lettuce
4
10
Leek
17
40
Peppers, green
4
10
Peppers, red
6
15
Radishes
4
10
Radish
4
10
Rhubarb
2
5
Brussels Sprouts
25
60
Beetroot
8
20
Red Cabbage
17
40
Cucumber
2
6
Sorrel
23
55
Sauerkraut
8
20
Salsify
29
70
Celery
13
30
Asparagus
10
25
Spinach
21
50
Tomato
4
10
Savoy
17
40
Zucchini
8
20
Onion
4
9


Dairy Products (100 g / 3.5 oz)
Purine
Uric Acid

Milk

0

0
Yogurt, plain
0
0
Curd Cheese
0
0
Camembert Cheese
13
30
Emmentaler Cheese
4
10
Fresh Cheese
0
0
Cream Cheese
5
13
Gauda Cheese
7
16


Are there foods that specifically cause a Gout attack?


Many chronic gout sufferers are almost always bordering a high level where any one meal can push them over the edge and into an attack. The combination of both a high purine AND high acid meal can prove to be too much. This is why many people believe that a specific food is the cause of their gout attack; however, it is usually just what happens to tip that "already full cup" over and into an attack.

You must bring your uric acid down to a manageable level in order to gain some flexibility in your diet. Once again, this is where vitamins and supplements are necessary to provide your body with all of the tools that are crucial to uric acid management. You must enhance the body's ability to fight this disease, and diet alone can make this a daunting task.


If low purine gout diets aren't the way to go, what is?


Healthy, low purine foods should always remain a part of the balance you are aiming for. The better option would be to focus more on pH balance, as a whole. pH balanced meals and lifestyles can further your quest for healthy cell protection, thereby reducing your overall uric acid load. pH balance also aids to reduce the inflammatory response in the body that sends your organs into a frenzy and allows uric acid to be freely stored to be "dealt with" later.

Acid/ Alkaline base has to be in balance. If not, our organs and bones often end up providing the alkaline buffers. This leads to chronic degenerative diseases. Remember, in order to remain healthy or improve your health, the ph of your body must be slightly alkaline.

We can and must further support our needs and alkaline buffers through vitamins and supplements.

ALKALIZING FOODS

VEGETABLES

Garlic
Asparagus
Fermented Veggies
Watercress
Beets
Broccoli
Brussel sprouts
Cabbage
Carrot
Cauliflower
Celery
Chard
Chlorella
Collard Greens
Cucumber
Eggplant
Kale
Kohlrabi
Lettuce
Mushrooms
Mustard Greens
Dulce
Dandelions
Edible Flowers
Onions
Parsnips (high glycemic)
Peas
Peppers
Pumpkin
Rutabaga
Sea Veggies
Spirulina
Sprouts
Squashes
Alfalfa
Barley Grass
Wheat Grass
Wild Greens
Nightshade Veggies


FRUITS Apple
Apricot
Avocado
Banana (high glycemic)
Cantaloupe
Cherries
Currants
Dates/Figs
Grapes
Grapefruit
Lime
Honeydew Melon
Nectarine
Orange
Lemon
Peach
Pear
Pineapple
All Berries
Tangerine
Tomato
Tropical Fruits
Watermelon

PROTEIN

Eggs
Whey Protein Powder (grass fed sources only with no sugar/fake sugars- stevia is fine)
Cottage Cheese
Chicken Breast
Yogurt
Almonds
Chestnuts
Tofu (fermented soy ONLY)
Flax Seeds
Pumpkin Seeds
Tempeh (fermented)
Squash Seeds
Sunflower Seeds
Millet
Sprouted Seeds
Almond Nuts
Pistachio Nuts
Avoid nuts packaged or roasted in oil



OTHER Apple Cider Vinegar
Bee Pollen
Lecithin Granules
Probiotic Cultures
Green Juices
Veggies Juices (homemade)
Organic Milk
(unpasteurized)
Mineral Water
Alkaline Antioxidant Water
Green Tea
Herbal Tea
Dandelion Tea
Ginseng Tea
Banchi Tea
Kombucha
Coconut oil (unrefined, virgin)


SWEETENERS

Stevia

SPICES/SEASONINGS

Cinnamon
Curry
Ginger
Mustard
Chili Pepper
Himalayan Salt
Miso
Tamari
All Herbs

ORIENTAL VEGETABLES

Maitake
Daikon
Dandelion Root
Shitake
Kombu
Reishi
Nori
Umeboshi
Wakame
Sea Veggies


ACIDIFYING FOODS

FATS & OILS Avocado Oil
Canola Oil
Corn Oil
Hemp Seed Oil
Flax Oil
Lard
Olive Oil
Safflower Oil
Sesame Oil
Sunflower Oil

FRUITS

Cranberries

GRAINS

Rice Cakes
Wheat Cakes
Amaranth
Barley
Buckwheat
Corn
Oats (rolled)
Quinoa
Rice (all)
Rye
Spelt
Kamut
Wheat
Hemp Seed Flour

DAIRY
Cheese, Cow
Cheese, Goat
Cheese, Processed
Cheese, Sheep
Milk
Butter


NUTS & BUTTERS Cashews
Brazil Nuts
Peanuts
Peanut Butter
Pecans
Tahini
Walnuts

ANIMAL PROTEIN

Beef
Carp
Clams
Fish
Lamb
Lobster
Mussels
Oyster
Pork
Rabbit
Salmon
Shrimp
Scallops
Tuna
Turkey
Venison

PASTA (WHITE)

Noodles
Macaroni
Spaghetti

OTHER

Distilled Vinegar
Wheat Germ
Potatoes


DRUGS & CHEMICALS Chemicals

Drugs, Medicinal
Drugs, Psychedelic
Pesticides
Herbicides

ALCOHOL

Beer
Spirits
Hard Liquor
Wine

BEANS & LEGUMES

Black Beans
Chick Peas
Green Peas
Kidney Beans
Lentils
Lima Beans
Pinto Beans
Red Beans
Soy Beans
Soy Milk
White Beans
Rice Milk
Almond Milk



ACID PRODUCING ACTIVITIES & EMOTIONS

Overwork
Anger
Fear
Jealous
Stress



How does excess weight/obesity affect Gout Attacks?


We know that overeating promotes the inflammatory response and suppresses the immune system. Obesity can affect the heart, blood flow, friendly bacteria levels and nutrient assimilation appointing excess strain on these organs and their essential functions. As a result, extra uric acid production is common. Moreover, the typical diet involved in obesity cases is rarely conducive to healthy uric acid balance.

Heavy, red-meat-based diets or lots of sugar-laden foods would definitely have a negative impact on immune function and promote inflammation, whereas calories in the form of fruits, vegetables, legumes, nuts and seeds would improve immunity.

It is known that even an extra 20 pounds can create an abundance of inflammation in the human body and lower overall immunity. Weight management is an important aspect of maintaining a balanced immune system and controlling inflammatory conditions such as Gout.

Is the Atkin's diet a problem for Gout sufferers? Are other fast weight loss methods problematic?

The Atkins Diet is a high protein and highly acidic approach to weight loss. This diet holds little to no alkaline balance, a balance essential to maintaining healthy body environment. Acidic body conditions allow for disease growth.

Consequently, diets like these can drastically increase your chances, and even directly contribute to, Gout and other degenerative disease development. Crash diets deplete the body of vital nutrients, creating an acidic body environment, and release stored purines from the body fat in the process. As you know, excess purine release results in even further uric acid production.

A healthy weight is essential to gout and disease control.

Fast and unnatural weight loss methods are dangerous to your health AND increase uric acid levels in the body. Purines are stored in fat cells. When they are released too quickly, overload is inevitable. Your body needs the time to slowly deal with the purine release in order to excrete it from the body and avoid even more uric acid production and storage.

Should I be eating low fat and fat free foods only?


Low fat and fat free foods are rarely recommended by us. In most cases, they aren't any "better", and can raise even more health concerns.

Most of these foods are chemically altered and processed to achieve the fat removal and often replaced with even more undesirable ingredients, like sugar, to enhance their taste. Fat restrictions can go way too far and can be equally as dangerous as a diet too heavy in all the wrong fats.


Low-Fat Diet Dangers



MedicineNet.com defines fat as follows: "along with proteins and carbohydrates, [fat is] one of the three nutrients used as energy sources by the body. The energy produced by fats is 9 calories per gram."

Fats are essential to our energy, our cell health, our mental health, the regulation of our hormones, our nutrient absorption, and more.





Health Risks Involved with Fat Restrictive Diets




  • Vitamin Absorption:

    Fat soluble vitamins such as A, D, E, and K require healthy dietary fats in order to utilize them properly. These vitamins are responsible for cell growth, immunity, blood clotting, and more. They are stored mainly in the liver and fat tissue and require proper fat intake to perform their bodily functions and avoid dangerous deficiencies.


  • Nutrient Imbalances:

    Diet balance is essential. When you reduce one area too much, such as fats, you will likely increase in other areas such as carbs and proteins. Carbohydrate-rich diets increase your risk of Diabetes II and typically inflates the appetite. High-protein diets place unhealthy strain on the liver and kidneys with its overly acidic qualities. Disease prevention and proper nutrition relies heavily on the balance of all three macronutrients.


  • Heart Disease:

    We need our HDL (the good) cholesterol levels to be high in order to fight heart disease. HDL collects the bad cholesterol, LDL, and carries it to the liver in order to be excreted from the body. When these ratios are imbalanced by way of a diet too low in fat, you face cholesterol problems and increase your risk for heart disease. Fatty acids, such as Omega-3's are essential to this necessary balance.


  • Mental Disorders:

    Essential fatty acids play a large role in our mental health, our moods and behavior. They directly affect the hormones and chemicals in our brain. Fat/diet imbalances have been linked to conditions such as depression, bipolar disorder, eating disorders, schiszophrenia, and ADHD.


  • Cancer:

    Low intake of essential fatty acids have also been linked to cancers such as prostate, breast, and colon. Omega-3 fats have been shown to slow the unhealthy cell and tumor growths.


  •  
  • Eating habits:

    Low-fat and fat-free foods can cause us to overeat empty calories. Because these foods are chemically altered and enhanced with sugars you'll often find the full-fat versions are very similar in calories. You are basically trading one overly processed and sugared version for a healthier option similar in caloric value. Make any sense? We don't think so. These empty calorie versions just make you crave even more, and in turn overeat because as a result. Choosing full fat versions can provide you the fullness and satiety needed to get your through to the next meal and avoid the processed low-fat versions that leave you hungry and craving for more.

    Not all fats are created equal. There are also some major misconceptions about saturated fats. Hint: They're not all evil! Foods such as avocados, coconut oil, raw nuts, olive oil (unheated), tuna, salmon, and raw seeds can be considered "healthy" fats. We even recommend full-fat sour dairy. Avoid trans-fats such as hydrogenated oils.

    What is the best way to test the pH of my body?


    By and large, blood pH is the most accurate way of measuring our health and body functioning. However, this cannot be done at home and is rarely done professionally, either. Urine and saliva pH test results can be rather telling about our overall health and the capability of uric acid excretion. This type of testing can be done at home.

    Test your urine over a 48 hour period, 4 to 6 times a day -- one upon waking one, 1 hour after breakfast, 1 hour after lunch, 1 hour after dinner and before bed. If you wake at night to urinate, we advise to test that one also. Record your results.
  • Is sugar a major contributor to uric acid problems?
    YES!! Fructose increases uric acid through a complex process that causes cells to burn up their ATP rapidly, leading to "cell shock" and increased cell death (remember 70% of uric acid production comes from the death of your cells!) After eating excessive amounts of fructose, cells become starved of energy and enter a state of shock, just as if they have lost their blood supply. Massive cellular die-off leads to increased uric acid levels.

    HCFS, or High Fructose Corn Syrup, is lurking in almost every processed food imaginable. According to Dr. Hyon Choi and colleagues from Boston University, drinking high fructose syrup laden beverages increases uric acid levels in the blood, which eventually deposits into the joints where it causes gout..


    How Can We Avoid HFCS (high fructose corn syrup)?
    The first food to go has to be the soft drinks; this includes fruit punch, fruit cocktails, and Kool-Aid since they are all laden with HFCS.

    Second, eat more meals at home. Restaurant foods are mostly prepackaged foods reheated and served to you. Use of HFCS in these foods is wide spread because of their increased shelf life.

    While shopping, read the labels, if HFCS, fructose, or modified corn starch appears within the first five ingredients place it back on the shelf an move on. Sounds easy right? Wrong. As you make your way through the store you will begin to realize just how much of what you have been eating on a daily basis contains HFCS.

    Reducing HFCS will not always be easy, but the health benefits are well worth it. You will feel stronger and more vital, it will lift your mood and give you increased concentration. Limiting your intake of HFCS will not only shrink your midsection, but also do wonders for your over all health.

    The Dangers of Too Much Sugar

    Fructose in Gout,
    Inflammation, and Disease


    The parallels between fructose and the increase in diseases such as Diabetes, Obesity, Gout and more, are virtually undeniable. Several decades ago the average American only consumed around 15g of fructose each day. Compare that to the average of 55g per day now consumed, with adolescents reaching upwards of 75g, and we may just have a strong link to the rise in inflammation and disease.

    Almost every cell in our body uses glucose for energy. When fructose fuses with glucose, sucrose is produced. Our livers are the only source capable of metabolizing fructose. Fructose cannot be used for energy by our body's cells. Therefore, high levels of fructose are seen and treated as a toxin in our body. As the liver breaks this down, an end product of that reduction is created in the form of a fat known as triglycerides. This fat can build up in the cells of the liver and cause damage to the liver. When this fat is released into the bloodstream, plaque on the artery walls begins to build.

    Fructose increases uric acid through a complex process that causes cells to burn up their ATP rapidly, leading to "cell shock" and increased cell death (remember 70% of uric acid production comes from the death of your cells!) After eating excessive amounts of fructose, cells become starved of energy and enter a state of shock, just as if they have lost their blood supply. Massive cellular die-off leads to increased uric acid levels. Uric acid can also shut down the production of nitric oxide, a substance needed to protect our artery walls from damage.

    Excess sugar can also cause insulin resistance, leptin resistance, addictive cycles of cravings, and binge eating. Some have attributed the "low-fat craze" of the 80's and 90's to the drastic increase in sugar consumption. Unfortunately, during these dietary guideline changes we traded some healthy fats for sugar, a trade that may have cost us our health.

    HCFS, or High Fructose Corn Syrup, is lurking in almost every processed food imaginable. According to Dr. Hyon Choi and colleagues from Boston University, drinking high fructose syrup laden beverages increases uric acid levels in the blood, which eventually deposits into the joints where it causes Gout.

    READ your food labels and steer clear of processed/boxed foods as much as possible. Often time, high-fructose corn syrup is the top ingredient. AVOID!! Avoid substitute sugars such as aspartame, sucrolose/splenda, saccharin, Acesulfame-K. Each is full of undesirable side effects and cancer-causing agents. Do your homework, they are pure poison!! Should you feel the need to sweeten any of your fresh foods, consider a natural sweetener such as Stevia.

    One should aim to stay under 25 grams of total fructose per day. This can add up quickly with processed foods and juices! Avoid your simple carbs as much as possible -- bread, pastry, pasta = sugar. Any sugar you do consume each day should come only/mainly from fruit. See our fructose chart to gain some perspective on how quickly 25g can add up with just fresh fruit alone:

    Fruit Serving Size Grams of Fructose
    Limes 1 medium 0
    Lemons 1 medium 0.6
    Cranberries 1 cup 0.7
    Passion fruit 1 medium 0.9
    Prune 1 medium 1.2
    Apricot 1 medium 1.3
    Guava 2 medium 2.2
    Date (Deglet Noor style) 1 medium 2.6
    Cantaloupe 1/8 of med. melon 2.8
    Raspberries 1 cup 3.0
    Clementine 1 medium 3.4
    Kiwifruit 1 medium 3.4
    Blackberries 1 cup 3.5
    Star fruit 1 medium 3.6
    Cherries, sweet 10 3.8
    Strawberries 1 cup 3.8
    Cherries, sour 1 cup 4.0
    Pineapple 1 slice
    (3.5" x .75")
    4.0
    Grapefruit, pink or red 1/2 medium 4.3



    Fruit Serving Size Grams of Fructose
    Boysenberries 1 cup 4.6
    Tangerine/mandarin orange 1 medium 4.8
    Nectarine 1 medium 5.4
    Peach 1 medium 5.9
    Orange (navel) 1 medium 6.1
    Papaya 1/2 medium 6.3
    Honeydew 1/8 of med. melon 6.7
    Banana 1 medium 7.1
    Blueberries 1 cup 7.4
    Date (Medjool) 1 medium 7.7
    Apple (composite) 1 medium 9.5
    Persimmon 1 medium 10.6
    Watermelon 1/16 med. melon 11.3
    Pear 1 medium 11.8
    Raisins 1/4 cup 12.3
    Grapes, seedless (green or red) 1 cup 12.4
    Mango 1/2 medium 16.2
    Apricots, dried 1 cup 16.4
    Figs, dried 1 cup 23.0
     


     

    Click to enlarge


      

    GOUT DIET AND GOUT SAFE
    FOOD -

    WHAT IS WRONG AND

    WHAT IS RIGHT?

    How does alcohol affect Gout?

     Alcohol, generally speaking, isn't
    high in 
    purines. However, alcohol
    is high acid and 
    adds to uric acid
    problems in other critical 
    ways.
    Beer may be the exception to
    this 
    rule as it happens to pose a
    double risk 
    with both high
    purine AND the high acid

    contributions.


  • Alcohol impedes removal of 
  • uric acid in the body. Alcohol 
  • is metabolized into lactic
  • acid in the body. The lactic acid
    then 
    competes with uric acid
    in the kidneys for 
    elimination
    through urine; thus, greater

    levels of uric acid remain in
    the body.

  • Alcohol contributes to uric acid 
  • levels in the body. Alcohol 
  • raises the amount of ATP that 
  • is converted into AMP- a good
  • foundation for uric acid.

  • Alcohol increases cellular 
  • degeneration within the body 
  • and the brain. As these
  • cells die off they release purines,
    which is 
    within every cell in our
    system.

    Additionally, alcohol consumption
    directly 
    affects and consumes the
    attention of the 
    liver and kidneys,
    impeding even more 
    uric acid
    excretion. Alcohol also 
    dehydrates
    the blood, further producing

    excessive uric acid.

    A recent study found that one
    alcoholic 
    beverage per day
    was enough to 
    significantly
    increase the risk of gout in

    that person. The risk grew as
    number of 
    drinks consumed
    increased.


    Am I drinking enough water 

    and why is this important to 

    Gout Control?


    Water consumption and the
    source for 
    your drinking water
    are both very 
    important.
    Unfortunately, a good portion
    of our society is dehydrated
    and isn't 
    even aware of it,
    which poses major 
    health
    risks.

    If the kidneys sense the body is
    becoming 
    too dry (water
    deficits), they begin to retain the
    fluid, 
    rather than excreting it as
    urine. This also 
    forces the body
    to hold onto excess uric 
    acid
    and other toxins ordinarily
    excreted by 
    the kidneys, and
    the damage begins. This 
    is a
    vicious cycle of dehydration.
    Proper 
    water intake is an
    essential key to blood 
    hydration and kidney filtration in
    order to 
    properly expel uric
    acid from the body
    .

    One should consume a pure
    source of 
    water, ideal amount
    for their body weight 
    and
    activity level, steadily
    throughout the 
    day. By the
    time you feel thirsty, you are

    already dehydrated. More 
    than 2 percent dehydration 
    and more.

    Daily Water Needs- Divide your
    bodyweight in 
    half. This is how
    many ounces of water 
    you need
    daily, consumed water at a slow
    but 
    steady pace from rise up
    throughout the day. 

     If you weigh 180lbs, divide 180
    by 2 = 90 oz of 
    water is needed
    , daily. Drinking water should
    come 
    from a pure source,
    preferably filtered for 
    purity and
    filters replaced according to

    manufactured suggestions.
    Optimal 
    drinking water pH is
    7.0. Juices, teas, 
    sodas and
    coffee DO NOT count towards

    your water needs!
    High Temperature,

    Low Humidity
    Associated With Gout Attacks.....
    (HINT HINT- DRINK MORE
    WATER!)



    Gout News and Research
    Archive


    University of Texas study 

    links meat to kidney 

    cancer


    NBC News MAGGIE FOX
    Nov 9th 2015

    Another study has shown
    people who eat more meat
    have a high 
    risk of cancer.
    This time, it's kidney cancer,
    researchers reported

    Monday.

    And it's not just people who
    eat red meat, as many other
    studies 
    have shown. People
    who eat more so-called white
    meat, such as 
    chicken, have
    the higher risk, too.

    Dr. Xifeng Wu and colleagues
    at The University of Texas MD

    Anderson Cancer Center in
    Houston studied 659 patients
    just 
    diagnosed with kidney
    cancer and compared them
    to 699 similar 
    people without
    cancer.

    They wanted to break down
    not just the link, but to tease
    out the 
    factors that might
    explain it. They looked at what
    kinds of meat 
    people ate, how
    they cooked it, as well as
    people's genetic 
    makeup to
    see if certain genes made
    them more susceptible.

    People who said they ate the
    most grilled meat -- red meat
    and 
    chicken alike -- had a
    higher risk of kidney cancer,
    they reported in 
    the journal
    Cancer. And those with two
    genetic mutations that

    already put people at higher
    risk of kidney cancer were
    most 
    affected by the grilled
    meat risk.

    People with kidney cancer
    also ate fewer fruits and
    vegetables than 
    people
    who didn't have it.

    "Although previous studies
    have linked meat intake with
    an 
    increased risk of (kidney
    cancer), to the best of our
    knowledge the 
    underlying
    mechanism for this
    association remains
    unclear," they 
    wrote.

    Cancer experts have long
    known that grilling or
    barbecuing meat 
    can make
    it carcinogenic. Burning or
    charring meat creates

    cancer-causing substances.

    In this case, the two culprits
    Wu's team looked for were
    2-amino- 
    1-methyl-6-phenyl-
    imidazo(4,5-b) pyridine
    (PhIP for short ) and

    amino-3,8-dimethylimidazo
    (4,5-f) quinoxaline
    (MeIQx for short).

    "Kidney cancer is among the
    10 most common cancers in
    both men 
    and women," the
    American Cancer Society
    said. The group projects

    that more than 61,000
    Americans will be diagnosed
    with kidney
     cancer this year
    and 14,000 will die of it.

    "For reasons that are not
    totally clear, the rate of new
    kidney cancers 
    has been
    rising since the 1990s,
    although this seems to have
    leveled 
    off in the past few
    years," the American Cancer
    Society added in a

    statement on its website.

    "Part of this rise was probably
    due to the use of newer
    imaging tests 
    such as CT
    scans, which picked up some
    cancers that might never

    have been found otherwise."

    Wu's team also wonders
    whether an increase in eating
    meat might 
    explain some of
    it.

    "The American/Western dietary
    pattern consists largely of red
    and 
    processed meats, and the
    results of the current study
    suggest that 
    the association
    between this dietary pattern
    and cancer may be in 
    part
    explained by exposure to
    meat cooking mutagens,"
    they 
    wrote.

    Last month, the International
    Agency for Research on
    Cancer (IARC) 
    released a
    controversial report that
    stated definitively that
    processed 
    meats such as
    sausages and bacon cause
    cancer and that red meat

    probably does.

    This study fits in with the
    studies that undergird the
    IARC's 
    pronouncement.

    Outside experts said it will be
    important to find out just
    what the risk 
    is and what
    people can do about it.

    "Once we have identified
    more genes we will likely
    be able to identify 
    a subset of
    the population that is at
    particularly high risk to
    develop 
    kidney cancer if they
    eat meat and processed
    meat," said Dr. Ulrike 
    Peters
    of the Fred Hutchinson
    Cancer Research Center
    in Seattle.

    "However, overall
    recommendations to limit
    intake of red and 
    processed
    meat will remain for the
    entire population."




    Gout and the 

    Antihypertensives


    Linda Brookes, MSc,
    Hyon K. Choi, MD, DrPH
    (summary below/

    full interview

    https://www.medscape.com/viewarticle/761761_3):



    Patients with hypertension,
    the incidence of gout has been
     calculated as 3 times higher
    than in non hypertension
    patients. Much of this added
    risk is attributed to the use of
    diuretics, which are
    associated with increased
    serum uric acid levels.
    Current hypertension
    guidelines recommend
    caution in the use of
    diuretics in elderly
    hypertensive patients or
    cite this adverse effect of
    diuretics as a possible
    contraindication in
    patients who may already
    be at risk for gout.

    Other, non-diuretic classes
    of antihypertensive drugs
    have also been shown to
    affect serum uric acid levels,
    which prompted Dr. Choi's
    group to examine the
    relationship between these
    drugs and gout in people with
    hypertension. To accomplish
    the analysis, these
    investigators used a
    database of computerized
    medical records generated
    by UK general practitioners
    between 2000 and 2007.
    The data came from 24,768
    incident cases of gout
    among adults aged 20-79
    years, 51.9% with a prior
    diagnosis of hypertension,
    and a random sample of
    50,000 matched controls.
    Dr. Choi reported that
    after adjusting for age,
    sex, body mass index
    (BMI), visits to the
    general practitioner,
    alcohol intake, and
    pertinent drugs and
    comorbidities, the relative
    risk of incident gout
    among patients with
    hypertension was reduced
    with use of calcium
    channel blockers. By
    contrast, the risk of gout
    was increased with use of
    diuretics, beta-blockers,
    angiotensin-converting
    enzyme (ACE) inhibitors,
    and non-losartan
    angiotensin II receptor
    blockers. Use of these
    drugs in the patients without
    hypertension produced
    similar results. In the patients
    with hypertension, there was
    a significant trend in relative
    risk reduction for gout with
    duration of CCB use and
    with losartan use.

    FDA approves another 

    dangerous gout drug


    by Michele Cagan at
    healthiertalk.com


    The FDA just approved IV drug
    Krystexxa for gout treatment.
    But they couldn't have possibly
    looked at the trial results. Or
    they just hate people with gout.

    The results were ridiculous...

    Fewer than half the people in the
    trial actually ended up with a
    positive response to the medicine
    --so it doesn't really seem to
    work. On top of that, Krystexxa
    produced some pretty nasty
    adverse reactions.

    41% of the patients suffered
    severe infusion reactions,
    despite taking antihistamines
    and steroids before their
    Krystexxa treatment.

    77% suffered from gout flare-ups,
    compared to 51% taking placebo
    --and that's despite being
    pretreated for at least a week
    with NSAIDs, colchicine, or both.

    Not to mention an unusually large
    percentage of anaphylactic
    reactions (again, despite
    premedicating with
    antihistamines and steroids!),
    and other very unpleasant side
    effects like chest pain, nausea,
    vomiting, and bruises.

    If you're suffering with gout, don't
    put yourself through even more
    suffering with Krystexxa.
    Especially when there are
    effective natural solutions that
    won't make your gout worse
    than ever. 



    The People's 

    Pharmacy- 

    Prednisone 

    Side Effects: 

    Deal With 

    The Devil?


    Prednisone (and similar
    corticosteroids) can be a life
    saving drug. It saved my
    sanity when I developed
    sudden hearing loss in one ear.
    That was a really scary
    experience for someone who
    depends on hearing to be able
    to do live radio. The ear, nose
    and throat specialist
    diagnosed my deafness as
    "idiopathic sudden sensor
    neural hearing loss." In other
    words, he didn't have a clue
    what caused it. He did 
    prescribe high doses of
    prednisone and within a
    few days my hearing returned.

    Similar corticosteroids
    like prednisone include:
  • Cortisone
  • Dexamethasone
  • Hydrocortisone
  • Methylprednisolone
  • Prednisolone


    There are many conditions for 
  • which such drugs can be 
  • extremely valuable, even 
  • life saving. Here are just a 
  • few:
  • Very serious allergic reactions 
  • (bad poison ivy for example)
  • Anaphylactic shock 
  • (life-threatening allergic 
  • reaction)
  • Brain tumors
  • Inflammatory bowel disease 
  • (Crohn's disease)
  • Severe asthma (usually to 
  • help control acute flare-ups)
  • Severe nausea of 
  • chemotherapy
  • High altitude sickness 
  • (when there is brain swelling)
  • Traumatic brain injury
  • Addison's disease
  • Rheumatoid arthritis, lupus 
  • and polymyalgia 
  • rheumatica (PMR)
  • Multiple sclerosis (MS)
  • Giant cell arteritis


    As useful as corticosteroids can 
  • be for a wide range of 
  • conditions, the drugs can 
  • also cause an extraordinary 
  • number of serious side
  • effects. Some people have
    likened this to a deal with the
    devil.
    Even short-term use can cause
    problems.

    The week or two that I took
    prednisone for my hearing loss
    I couldn't sleep, became
    incredibly irritable and hard to
    live with, and felt as if I had
    turned into someone I didn't
    know or like. A study in the
    American Journal of
    Psychiatry analyzed data from
    hundreds of thousands of
    European patients over an 18
    year period. They discovered
    that people taking
    corticosteroids were more
    likely to experience neuro
    psychiatric symptoms
    including depression, suicidal
    thoughts (and actions),
    delirium, disorientation,
    confusion, panic and manic
    episodes. The authors
    conclude that:
    "Glucocorticoids [another
    term for corticosteroids]
    increase the risk of
    suicidal behavior and
    neuropsychiatric disorders.

    Educating patients and their
    families about these adverse
    events and increasing primary
    care physicians' awareness
    about their occurrence should
    facilitate early monitoring."

    +++++++++++++++++

    I can relate. I certainly felt
    disoriented and out of control
    on the relatively high dose I was
    taking. The trouble is that
    patients and their families are
    not always warned about such
    side effects. Here are some
    scary stories that have been
    reported to this website:

    +++++++++++++++++

    Years ago I was given prednisone
    in the emergency room for a
    severe anaphylactic reaction that
    affected my ability to breathe
    and caused massive hives.
    Although the treatment may have
    been necessary, I too had a
    severe psychotic reaction and
    when I finally went to my own
    doctor and had blood tests, my
    blood chemistry was all over
    the map. I had to continue the
    tapered dose till I was done but
    I wish someone had warned me
    of possible side effects so at
    least I wouldn't think I was totally
    crazy. "I questioned my ability
    to drive, slept constantly, and
    was quite volatile. I had to take
    a day off from work. Knowledge
    is power! People should be
    warned about possible side
    effects so they have the
    information should side effects
    occur." AC

    +++++++++++++++++

    "I was on 20mg twice a day of
    prednisone for a sinus infection.
    Had I known anything about this
    horrible drug I would have never
    taken the meds and let my sinus
    infection clear up on its own.
    That would have been better
    than these side effects.

    "I was not told to taper the dose,
    so I took as prescribed 20mg
    twice daily for 7 days. The day
    after stopping my whole body
    hurt to the touch, as if I was
    black and blue all over. I was
    swollen, red and had a lump on
    my neck, not to mention being
    very disoriented. I went back to
    the doctor and he insisted this
    had nothing to do with the
    drug. "I checked myself into the
    ER where they put an IV drip
    with benadryl and the like. I was
    discharged that day. No change.
    Next day, didn't hurt to the
    touch anymore. New side effect
    - rash from head to toe and
    severe indigestion. Following
    day, rash subsiding, indigestion
    getting better. Still feeling a bit
    loopy, but I am told by next
    week I should be back to
    myself again.

    "I am warning everyone I know
    not to ever take a steroid
    unless your life is in danger.
    It is a very scary feeling - all for
    a sinus infection."
    AMS

    +++++++++++++++++

    I'm having Prednisone side effects.
    My doctor prescribed this drug
    last Thursday. She prescribed 20
    mg twice daily for five days. I was
    sleepless for three days in row.
    On day 4 after a short nap I awake
    feeling so nervous. I am crying, my
    hands are shaking, and my heart is
    beating so hard. These are awful
    feelings.

    "My doctor told me I will feel that
    way for about nine days. She
    didn't show any care about me.
    She also
    said I can go back to work (and
    drive a long way) the next day.
    But the way I was and am
    feeling I'm not daring to drive
    even one block.

    "I do not understand why she
    prescribed that medicine,
    without any warning, for a
    small allergy I had. I mean the
    medicine was worse than my
    illness." ELY

    +++++++++++++++++

    "My wife had sleepness nights
    when on prednisone and the
    doctor said that she might do
    some odd things that she
    normally wouldn't do. He was
    right. One night she got up and
    tore down the wall paper in our
    bathroom :-) We still get a
    laugh over this one."
    Bob K.

    +++++++++++++++++

    "I am experiencing high blood
    pressure, agoraphobia, panic
    attacks, light headedness,
    confusion, weakness,
    intolerance to heat, IBS, shaking,
    etc. These side effects all
    started the day I stopped the
    drug. It has been 7 days with
    not much improvement. I was
    hospitalized for 3 days. I pray I
    do not EVER have to take
    prednisone again... EVER. "I
    am hoping I get past this. My
    quality of life stinks. I took
    30mg 1 day, 20mg 2 days and
    1 mg 2 days.
    Absolutely HATE this." SKF

    +++++++++++++++++

    These are just some of the
    messages that have been
    posted to our website. Feel free
    to add your story or comment
    below. We find it astonishing
    that some prescribers do not
    warn patients about the
    possibility of psychological side
    effects brought on by
    prednisone and friends. Even a
    short-course of high-dose
    steroid can precipitate
    symptoms. And not warning
    about gradual tapering borders
    on bad medicine. To protect
    yourself and your loved ones
    from such medical mistakes
    we suggest our latest book,
    Top Screw-ups Doctors Make
    and How to Avoid Them.


    ABOUT TOP SCREWUPS
    DOCTORS MAKE AND HOW
    TO AVOID THEM

    A primary care doctor is
    skeptical of his patient’s
    concerns. A hospital nurse or
    intern is unaware of a drug’s
    potential side effects. A
    physician makes the most
    “common” diagnosis while
    overlooking the signs of a rarer
    and more serious illness, and
    the patient doesn’t see the
    necessary specialist until it’s too
    late. A pharmacist dispenses
    the wrong drug and a patient
    dies as a result.
     
    Sadly, these kinds of mistakes
    happen all the time. Each year,
    6.1 million Americans are
    harmed by diagnostic mistakes,
    drug disasters, and medical
    treatments. A decade ago, the
    Institute of Medicine estimated
    that up to 98,000 people died in
    hospitals each year from
    preventable medical errors. And
    new research from the University
    of Utah, HealthGrades of Denver,
    and elsewhere suggests the toll
    is much higher.
    Patient advocates and
    bestselling authors Joe and
    Teresa Graedon came face-to-
    face with the tragic
    consequences of doctors’
    screwups when Joe’s mother
    died in Duke Hospital—one of
    the best in the world—due to a
    disastrous series of entirely
    preventable errors. In Top
    Screwups Doctors Make and
    How to Avoid Them, the
    Graedons expose the most
    common medical mistakes,
    from doctor’s offices and
    hospitals to the pharmacy
    counters and nursing homes.
    Patients across the country
    shared their riveting horror
    stories, and doctors recounted
    the disastrous—and sometimes
    deadly—consequences of their
     colleagues’ oversights and
    errors. While many patients feel
    vulnerable and dependent on
    their health care providers, this
    book is a startling wake-up call
    to how wrong doctors can be.

    The good news is that we can
    protect ourselves, and our loved
    ones, by being educated and
    vigilant medical consumers.
    The Graedons give patients the
    specific, practical steps they
    need to take to ensure their
    safety: the questions to ask a
    specialist before getting a final
    diagnosis, tips for promoting
    good communication with your
    doctor, presurgery checklists,
    how to avoid deadly drug
    interactions, and much more.
               
    Whether you’re sick or healthy,
    young or old, a parent of a young
    child, or caring for an elderly
    loved one, Top Screwups
    Doctors Make and How to Avoid
    Them is an eye-opening look at
    the medical mistakes that can
    truly affect any of us—and an
    empowering guide that explains
    what we can do about it.



    We want to emphasize that
    corticosteroids can be very
    valuable.
    Some people must take them for
    the rest of their lives because of
    a very serious or life-threatening
    condition. And NO ONE should
    ever stop taking a drug like
    prednisone suddenly. It must
    be phased off gradually under
    medical supervision.

    Here are some other side effects
    associated with corticosteroids.

  • Fluid retention, edema
  • Insomnia
  • Irritability, nervousness, mood 
  • swings, mania, depression, 
  • psychosis
  • Disorientation, confusion
  • Hypertension
  • Loss of potassium
  • Headache
  • Dizziness, vertigo
  • Muscle weakness
  • Bloodsugar elevation(diabetes)
  • Irregular menstrual cycles
  • Swollen face
  • Hair growth (including on the 
  • face)
  • Itching, rash, hives
  • Increased susceptibility to 
  • infection
  • Weakened bones (osteopenia, 
  • osteoporosis)
  • Tendon rupture
  • Glaucoma
  • Cataracts
  • Ulcers


    The higher the dose and the 
  • longer someone takes a drug 
  • like prednisone the more 
  • likely there will be side 
  • effects. Make sure your 
  • physician is monitoring 
  • things like potassium, blood 
  • sugar, bone density and 
  • psychological well being. And 
  • never stop a corticosteroid 
  • suddenly!

  • Joe Graedon, for
    The Soapbox blog on
    The People's Pharmacy



    BBC news Sunday, 

    9 May, 2004 - Gout

    treatments 'remain 

    unproven'


    There is little scientific evidence
    to support the use of some
    current treatments for gout,
    researchers say. The condition
    is usually treated with an anti-
    inflammatory drug, or with
    alternatives such as steroids.

    But the journal Drug and
    Therapeutics Bulletin
    says
    much of the evidence for their
    effectiveness is anecdotal.
    Other experts have disputed
    that claim.

    Gout affects around 600,000
    people in the UK and is
    becoming increasingly
    common in men.

    Gout generally involves very
    severe attacks of joint pain
    followed by long periods of
    remission.

    The condition is caused by the
    formation of urate crystals
    within joints and other tissues.

    Acute attacks are usually treated
    with an anti-inflammatory drug -
    in many cases indometacin.

    However, the DTB says there are
    no published studies showing
    whether this is the most
    effective treatment.

    In fact, it says there is evidence
    to suggest that indometacin is
    no better, or more easily
    tolerated than other anti-
    inflammatory drugs.

    Some people - for instance those
    with stomach ulcers - cannot
    take anti-inflammatory drugs.

    In these cases doctors rely on
    alternative treatments such as
    colchicines and steroids.

    However, the DTB says their use
    is based more on anecdotal
    experience than on published
    research.

    Prevention

    The journal also raises questions
    about preventative drugs
    commonly prescribed to many
    patients to try to stop further
    attacks - drugs, which in many
    cases, may be taken for years.

    Again, the journal says there is
    little published evidence on the
    effectiveness of such treatment.

    It says patients, rather than GPs,
    should make the decision on
    whether and when to start to
    take such medicines long term.

    Joe Collier, editor of Drug and
    Therapeutics Bulletin
    , said: "It is
    astonishing that we know so
    little about how best to treat the
    common (and very painful)
    condition gout.

    "The drugs used are old, so there
    is no drive to do the necessary
    research. This is an
    unacceptable position and
    needs remedying."

    The journal says there is some
    evidence to suggest that
    adopting a healthy lifestyle can
    cut the frequency of acute gout
    attacks.

    Shedding excess weight and
    avoiding high alcohol
    consumption are all thought to
    help.

    Claims disputed

    But Dr Michael Snaith, a
    consultant rheumatologist in
    Derbyshire and expert on gout,
    told BBC News Online that the
    criticism of current treatments
    had been over-egged.

    He said it was true to say that
    different anti-inflammatory
    drugswere equally effective at
    treating gout - but he said that
    as a group they were a highly
    effective way to combat the
    condition.

    "Most developments in gout
    occurred in the middle third of
    the last century before electronic
    databases were set up - these
    researchers may not have gone
    back far enough," he said.

    "For instance, there is
    undoubtedly hard evidence of
    the effectiveness of Allopurinol,
    a drug developed to treat cancer
    in the 1950s, preventing gout
    attacks by reducing uric acid
    levels." 


    (NaturalNews) Drug 

    side effects left 

    woman blind and 

    scarred


    A federal jury has ordered Mutual
    Pharmaceutical Co. to pay $21
    million to a woman who was
    blinded and scarred in an
    adverse reaction to an anti-
    inflammatory drug.

    In January 2005, Karen Bartlett of
    Pliastow, NH, began taking a
    non-steroidal anti-inflammatory
    drug (NSAID) known generically
    as sulindac in order to relieve
    chronic shoulder pain. Sulindac
    is also marketed by Merck as
    Clinoril, and is in the same drug
    family as aspirin, ibuprofen and
    naproxen.

    Two weeks after beginning the
    drug, Bartlett began to suffer
    irritation around her eyes and
    noticed red spots developing on
    her face. Two days later,
    suffering from a still-worsening
    rash and feeling as if she had
    pebbles in her throat and under
    her eyelids, she was admitted
    to the hospital.

    Doctors diagnosed her with a
    potentially fatal skin disease
    known as Stevens-Johnson
    Syndrome and Toxic Epidermal
    Necrolysis (SJS/TEN),
    characterized by inflammation
    of the eyes and mucus
    membranes. SJS/TEN can
    produce rashes so severe that
    the body's entire outer layer of
    skin is burned off.

    Bartlett spent 112 days in five
    different hospitals as the disease
    continued to burn away her skin
    and the tissue from her throat,
    stomach and lungs. Although
    she did survive, she was left
    permanently disabled and
    legally blind.

    "It literally burned her alive," her
    lawyer Keith Jensen said. "It
    burned 65 percent of the skin
    off her body ... It burned her
    inside and out."

    SJS/TEN is a known potential
    side effect of all NSAID drugs,
    but sulindac carries the highest
    risk of it.

    "Before you start taking common
    ... drugs, you may need to inform
    yourself about this often-fatal
    reaction," writes Andreas Moritz
    in Timeless Secrets of Health
    & Rejuvenation
    .

    "The list of drugs that may be
    problematic includes
    antiepileptic and anticonvulsant
    drugs, sulfonamides, ampicillin,
    allopurinol and [NSAIDs], as
    well as some vaccinations
    (such as anthrax)."


    Colchicine side effects, 

    nutrient depletions,

    herbal interactions 

    and health notes:

    Data provided by Applied Health

  • Vitamin B12 levels may be 
  • depleted with long term use 
  • of the drug.1

  • Colchicine may lower 
  • potassium, sodium and 
  • vitamin A levels.2

  • Colchicine has been linked to 
  • impaired absorption of Beta-
  • Carotene.
  • Individuals taking colchicine
    would most likely benefit from
    taking a high-potency
    multivitamin/mineral supplement
    to compensate for these
    interactions.3


  • Colchicine interferes with 
  • vitamin B12 metabolism by 
  • reducing
  • intrinsic-factor-B12 receptors.
    Despite uncertainty about the
    exact relationship, caution is
    indicated in elderly individuals
    taking colchicine and
    experiencing nervous system
    symptoms. Any evidence of
    neuropathies following the use
    of colchicine warrants checking
    serum levels of B12 for
    deficiencies. B12
    supplementation
    would be judicious
    prophylactically and
    administration is indicated when
    any deficiency is detected. A
    generous and wholly safe
    dosage of 10-25 mcg per day
    of vitamin B12 would
    compensate for the adverse
    effects of taking colchicine.
    Periods testing of serum levels
    would be appropriate for
     monitoring vitamin B12 status.

  • Colchicine has been linked to 
  • impaired absorption of 
  • Magnesium.
  • Individuals taking colchicine
    would most likely benefit from
    taking a high-potency multi
    vitamin/mineral supplement to
    compensate for these
    interactions.5


  • Dietary Fat. A variety of 
  • studies indicate that 
  • colchicine interferes with the 
  • intracellular phase of fat 
  • absorption.6


  • Colchicine has been linked to 
  • impaired absorption of 
  • lactose. In studies of patients 
  • with familial Mediterranean 
  • fever (FMF) Fradkin et al 
  • found that colchicine 
  • induces significant lactose 
  • malabsorption in FMF 
  • patients and concluded that 
  • this interaction was at least
  • partially responsible for the
    gastrointestinal side effects of
    the drug.7


  • Tannin containing plants: 
  • Atropa belladonna, Lobelia 
  • inflata can interfere with 
  • colchicine8


  • Herbs high in salicylates 
  • (aspirin-like compounds) can 
  • precipitate herbal alkaloids 
  • and impair absorption of 
  • colchicine. Herbs high in
  • salicylates should not be taken
    with colchicine.9


  • Herbs containing Tannins such 
  • as Camellia sinensis(GreenTea
  • and Black Tea), Arctostaphylos
    uva-ursi (Uva ursi), Juglans nigra
    (Black Walnut), Rubus idaeus
    (Red raspberry), Quercus spp.
    (Oak), and Hamamelis
    virginiana (Witch Hazel)
    Herbs high which yield tannins
    when extracted by hot water
    can precipitate alkaloids which
    can impair absorption of
    colchicine. Tannins will not
    precipitate low concentrations
    of alkaloidal salts in the
    presence of many gums present
    in plants such as Acacia, Agar,
    Aloe, Flax, Guar, Irish moss,
    Locust bean, Marshmallow root,
    Okra fruit, pectin powder,
    Psyllium seed husks and
    Slippery Elm bar. Herbs high in
    tannins should not be taken
    with colchicine. 10



    Dangers of low-dose 

    colchicine in patients

    with renal failure



    [No authors listed]

    Abstract

    (1) Life-threatening colchicine
    intoxication can occur in
    patients with renal failure, even
    with low-dose regimens.

    (2) Diarrhea, nausea and
    vomiting are the first
    manifestations of overdose.
    Colchicine must be withdrawn
    immediately to avoid severe
    complications (especially
    haematological and
    neuromuscular).

    (3) Colchicine must not be
    prescribed without first
    assessing creatinine clearance
    (using the Cockroft formula,
    for example),
    especially in elderly patients.



    (New Zealand Herald) 

    Medsafe's inability to

    act on gout drug seen 

    as dangerous

    loophole

    New Zealand's medicines
    regulator has a "serious safety
    concern" over a gout drug that
    has won state funding, but is
    powerless to initiate a safety
    review.

    This has been described as a
    dangerous loophole in the
    Medicines Act.

    Gout is a form of arthritis that
    can cause excruciating pain in
    joints, particularly the big toe.

    In April, Pharmac approved
    funding for benzbromarone -
    even though it has not gone
    through the separate medicines
    registration process with the
    regulator, Medsafe.

    The drug was withdrawn in
    Europe in 2003 because of
    serious liver toxicity, including
    one death.

    The Centre for Adverse Reactions
    Monitoring has notified Medsafe
    of a gout patient taking the drug
    who was also on the blood-
    thinner warfarin. The gout drug
    can enhance the blood-thinning
    effect of warfarin and the
    patient suffered bleeding.

    "Medsafe considers this to be a
    serious safety concern ... ," a
    Medsafe official said by email
    to Lance Gravatt, whose
    company imports a rival gout
    drug. "Benzbromarone is not an
    approved medicine in New
    Zealand and therefore the
    regulator's legislative powers
    do not apply," the official said.

    "In practice, this means Medsafe
    is unable to refer this medicine
    to the MARC [Medicines Adverse
    Reactions Committee] to
    conduct a benefit/risk review or
    take any regulatory activity."

    Instead, Medsafe will publish an
    "alert" next week in its Prescriber
    Update newsletter to remind
    doctors the gout drug is known
    to interact with warfarin. It will
    also point out that although
    there is no New Zealand
    datasheet on the drug on the
    Medsafe website - normally a
    key source of drug-safety
    information for doctors - it is
    listed on the online NZ
    Formulary.

    Unregistered medicines can still
    be legally used, but doctors who
    prescribe them carry more
    complex responsibilities than
    usual to explain the risks and
    benefits, and obtain full
    informed consent from the
    patient.

    Dr.Gravatt said Medsafe's inability
    to initiate a safety review was a
    loophole that created risks for
    patients. "We are alarmed at this
    situation, notwithstanding our
    conflict of interest in being the
    supplier of an unfunded
    [although registered] gout
    treatment.

    "With no datasheet or consumer
    medicine information, are we
    really to believe that GPs will
    search the National Formulary
    every time?"

    Australian gout expert Professor
    Richard Day said it was good the
    Pharmac application form for
    doctors who wanted to prescribe
    benzbromarone highlighted the
    risk of liver toxicity. But warfarin
    should be highlighted too, as
    should the need for extra
    monitoring if patients were
    taking the blood-thinner.

    Pharmac's medical director, Dr
    Peter Moodie, said that before
    listing the drug in April, the
    agency had approved funding
    case by case for many patients
    with "very severe gout - to the
    extent that the alternative is
    amputation in some cases".

    Pharmac funded 48 unregistered
    medicines.

    When asked if Pharmac carried
    greater drug-safety
    responsibilities when it funded
    an unregistered medicine, Dr
    Moodie said regardless of a
    drug's registration status,
    doctors were obliged to tell
    patients of risks and benefits,
    other-drug interactions, and
    obtain informed consent.

    What is gout?


  • A form of arthritis

  • Can be highly painful and lead 
  • to joint damage and disability

  • Prevalence estimate: 2.7 per 
  • cent of the population

  • More common in men, Maori 
  • and Pacific people

  • Causes include genetic 
  • inheritance, excess weight 
  • and alcohol intake, certain 
  • foods and drinks
  • - NZ Herald (by Martin Johnston)


    More bad news 

    about bread


    Bette Dowdell
    @healthiertalk.com


    Mercy, Maude, this bread mess
    is something else!

    In my article, Two Problems
    WithBread,I talked about celiac
    disease and bromide problems.
    Now I'm back with more bad
    news, additional bread
    ingredients you don't want
    anything to do with.

    Most bread lists Malted Barley
    Flour as an ingredient, typically
    the second one which means
    it's the second most prevalent
    ingredient. Translated? There's
    a bunch of it in there, and it's
    bad stuff.

    How's that, you ask? Well, malted
    barley flour comes loaded with
    the amino acid glutamate, an
    excitotoxin. That is, it can rev up
    the hypothalamus part of the
    brain to toxic levels, leaving it a
    wounded warrior.

    Now, this is a very bad thing
    seeing as how the hypothalamus
    controls your nervous system
    AND your endocrine system.
    When it gets wounded, so do you.
    Count on it.

    You may not connect that to your
    autoimmune disease, but you
    should. Same with a punked out
    thyroid. Or any other endocrine
    gland. Not to mention
    neuropathies, the pins and
    needles pain that seems to have
    no explanation.

    And, as if brain damage isn't
    enough, malted barley flour
    contains a ton of tannins, a
    major cause of migraines.

    Most commercial breads and
    bags of flour contain malted
    barley flour. Ya gotta read
    labels! And if there's no label
    to read, as in a restaurant?
    Assume it's there.

    They say malted barley flour
    improves the taste. Stomping
    all over your health isn't
    mentioned.

    Malted barley is also in some
    beers, with the same effects.

    Then there's azodicarbonamide
    (ADA). It's a pesticide from China
    that's added to flour to speed up
    the bleaching process.

    This is a biggy and getting bigger.
    While typically the last ingredient
    listed on labels, even a little
    packs a wallop.

    PesticideInfo.org links it to
    cancer, reproductive and
    developmental problems, nerve
    damage and overall toxicity.
    Yikes!

    Well, is there enough of it in
    bread to do any real damage?
    Oh, indeedy!

    It causes coughs, headaches
    that can last for days, shortness
    of breath, wheezing, swollen
    nasal cavities, burning throat
    and breathing problems. People
    report being diagnosed with
    asthma because of ADA. Quit
    the ADA, and they're healed!
    Same with sinus infections.

    The United Kingdom, Singapore,
    Australia and most of Europe
    ban ADA. The FDA and World
    Health Organization say it's just
    hunky-dory. No problem here.
    Move along.

    Subway, Dunkin' Donuts and
    Burger King all add ADA to their
    bread. MickyD's apparently
    doesn't.

    And don't buy any bread that's
    fortified with iron. They make it
    sound as healthful as all get
    out, but it's illegal in most of
    Europe because it triples the
    incidence of liver cancer.
    Besides, too much iron rusts us
    out. It also leads to heart
    problems.

    Finally, high fructose corn syrup.
    I'm worn out from all my jumping
    up and down about HFCS, so I'll
    just recap: HFCS raises
    triglyceride levels, leads to
    obesity and diabetes, raises
    uric acid levels (can you say
    gout?)
    , damages the kidneys,
    wears out the liver and creates
    general mayhem. Poison.

    Some people hope Ezekiel bread,
    said to be from a Bible recipe, is
    the answer. Sorry. Ezekial bread
    contains soy. Soy is a poison.
    Again, I'll summarize: Soy
    disrupts the endocrine system,
    causes kidney stones, strips us
    of the minerals we need,
    damages the hypothalamus,
    depresses the thyroid and
    eventually leads to breast and
    prostate cancers. And the thing
    is, it didn't exist in Bible lands
    during all the centuries in which
    the Bible was written.

    I love bread. I love the taste, the
    texture in my mouth, everything
    about it. I just wish they didn't
    mess with it so much.

    How to get sick and 

    die early


    Bette Dowdell
    @healthiertalk.com

    From time to time, subtlety gets
    in the way of a clear message.
    To forestall that unhappy
    possibility, permit me to write
    bluntly.

    Your health needs this message.

    If you eat or drink anything with
    high fructose corn syrup in it,
    you're stupid.

    If you're dealing with diabetes -
    and eat or drink anything with
    high fructose corn syrup in it -
    you're an idiot.

    If you're trying to lose weight -
    and eat or drink anything with
    high fructose corn syrup in it -
    you don't have a lick of sense.

    Smart up and avoid high
    fructose corn syrup (HFCS).
    Now, this takes vigilance. Lots
    of vigilance. That stuff is
    everywhere.

    It's in ketchup. Worcestershire
    sauce. Cereals. Bread.
    Processed foods. And on, and
    on. Reading food labels can be
    an eye-opening experience.

    Why should you bother? Let me
    count the ways.

    One can of soda pop contains
    enough HFCS to overwhelm your
    liver. Doing in your liver makes
    you a goner all by itself, but that
    can of soda starts a domino
    effect amongst your body parts.

    HFCS raises your triglycerides,
    the fatty acids in your blood.

    Not wanting to be left out, your
    blood pressure makes a leap.

    And your uric acid, confused by
    the never-seen-in-nature HFCS,
    starts an upward trek. Can you
    say gout?

    And now they're learning that
    high uric acid levels do a
    number on your kidneys. Whilst
    you pour HFCS down your gullet,
    you should at least have the
    good manners to wish your
    kidneys good luck.

    But, wait! There's more! HFCS
    sends your leptin into orbit. We
    know leptin as a big player in
    appetite and weight loss, but
    that pales in comparison to
    what it does to your brain and
    your pancreas.

    HFCS is murder on your
    pancreas. Charged with the task
    of maintaining blood sugar
    levels, the pancreas throws in
    the towel.
    See the sentence about diabetes
    above.

    Well, I could go on, but if you
    don't have the picture by now,
    why bother? Just eat, drink and
    be merry-and get sick and die
    early.

    Here's how it is: Your body
    doesn't know how to handle
    HFCS.
    It's like lobbing a bomb into
    your system.

    The manufacturers of HFCS
    know this, but it's the money,
    honey.
    How much money? More than
    enough to hire "researchers" and
    writers to sing the praises of
    HFCS so people think it's not
    so bad after all. To believe it's
    'natural'. That all's well with the
    world.

    But no matter how loudly they
    toot the bugle and bang the
    drum, HFCS manufacturers still
    couldn't sell the stuff if food
    manufacturers didn't happily
    jump on board.

    But here's the secret: Food
    manufacturers would quit the
    game, stop the HFCS nonsense
    on a dime, if you refused to buy
    the stuff.

    Bottom line: You get to choose
    whether or not to be an idiot.
    Is this a great country or what?



    High fructose 

    beverages 

    tied to gout


    Jonathan Benson
    @naturalnews.com

    (NaturalNews)
    New research derived from the
    larger Nurses' Health Study has
    found a new connection
    between drinking fructose-rich
    beverages like soda and
    developing joint arthritis.
    According to Dr. Hyon Choi and
    colleagues from Boston
    University, drinking high fructose
    beverages increases uric acid
    levels in the blood, which
    eventually deposits into the
    joints where it causes gout.

    Published in the Journal of the
    American Medical Association,
    the report claims that people
    who drink one fructose-rich
    beverage a day are 74 percent
    more likely than those who drink
    less than one per month to
    develop gout. And those who
    drink two or more fructose-rich
    beverages a day are 97 percent
    more prone to the disease than
    minimal drinkers.

    Strangely enough, even orange
    juice appears linked to gout.
    Once-a-day orange juice
    consumption raised risk levels
    by 41 percent, while drinking
    two servings a day resulted in
    a 142 percent risk increase.
    However, other kinds of juices
    did not appear to exhibit the
    same effects.

    "Physicians should be aware of
    the potential effect of these
    beverages on the risk of gout,"
    explained Choi and
    colleagues in their report.

    The team also noted that
    women with a body mass
    index (BMI)above 30, as well
    as those who drink alcohol,
    are at an even higher risk. And
    even though only one percent
    of women who participated in
    the study ended up developing
    gout, excess fructose
    consumption is never a good
    idea because the sugar
    component in its processed
    form can aggravate proper
    insulin function, induce type-2
    diabetes, and lead to obesity.



    Health Basics: 

    Processed 

    'vegetable' oils

    fuel inflammation 

    and cancer


    S. D. Wells
    @naturalnews.com

    (NaturalNews) What if you bought
    a brand new car or truck and you
    immediately filled it with used oil
    and ethanol-laden gasoline? How
    soon would you experience major
    engine malfunctions, and how
    soon compared to a new car that
    you gave only the cleanest oil
    and gas possible? Many people
    perceive vegetable oils as
    healthy, but excessive
    consumption of vegetable oils
    leads to actual structural
    changes within our fat stores
    and within our cell membranes.
    How are so many people fooled
    into ingesting large amounts of
    processed and pesticide-
    contaminated oils that kill them
    slowly? Is it because of the word
    vegetable or is it because of the
    term all natural that the "sheeple"
    (misled and uneducated people)
    pour in the hydrogenated
    rapeseed oil and the hexane
    vapor-laden polyunsaturated
    "dirty fuel"?

    Vegetables are good for you,
    right? Shouldn't vegetable oil be
    good for your organs and your
    blood? What if it's cold-pressed!?
    What's if it's "extra virgin"? What
    if you don't cook it at high heat?
    What if you do? These are the
    pressing questions that have
    Americans confused and running
    on saturated toxic fat and empty
    calories.

    Fatty acids have taken on a new
    dimension over the past 75 - 85
    years, like never before in the
    evolution of man and woman.
    Vegetable oils are being run
    through processes that lessen
    the acid, add toxic vapors, kill
    the nutrients, add in genetically
    modified (GM) proteins and
    enzymes, and confuse human
    cells, often choking them and
    breaking down their defenses.
    Some oils actually shut down
    the mechanism of life in cells,
    and mitochondria are
    suffocated to death. This leads
    to direct physiological changes
    and contributes to multiple
    diseases.

    Soybean oil, sunflower oil, corn
    oil, canola oil, cottonseed oil,
    safflower oil and the list goes on
    and on and on. They all sound
    like you might even be eating
    healthy, but it's time to wake up
    and smell the GMOs. Olive oil, if
    it's real and cold-pressed, can be
    good for you, but as soon as
    you cook it at high heat, you're
    in trouble. Grape seed oil is said
    to tolerate high heat, but you're
    about to find out why that
    doesn't even matter. Dead food
    is dead food, and it doesn't
    matter how long you cook it or
    how hot the fryer gets. At that
    point, all you're doing is adding
    to toxicity, not making it "healthy."
    Most oils contain very large
    amounts of biologically active
    fats called omega-6
    polyunsaturated fatty acids,
    which are quite harmful in
    excess.

    Industrial food oil processing is
    very scary - take a look

    In just 80 years, consumption of
    soybean oil increased a
    thousand-fold in the United
    States. When Monsanto figured
    this out, in came pesticide food
    for the masses. Using industrial
    chemicals and highly toxic
    solvents, most vegetable oils are
    processed until useless and
    sold as food. The omega-6
    overload messes up the fatty
    acid composition of the body.
    Currently, most Americans'
    ratios of omega-6 to omega-3 is
    around 16 to 1. This ratio
    basically cripples your immune
    system, and Big Food and Big
    Pharma both know it. This is
    the number one reason why
    eating out at restaurants is bad
    news. The excess of these fatty
    acids sits in cell membranes
    and increases harmful oxidative
    reactions. Typical body fat
    stores of linoleic acid have
    increased three-fold in just a
    few decades.

    GMOs and processed oils fuel
    inflammation


    Eicosanoids (also spelled
    icosanoids) are modified fatty
    acids in your cell membranes
    that play a crucial role in cellular
    messaging, immunity and
    inflammation. Aspirin and
    ibuprofen inhibit the eicosanoid
    pathways and artificially reduce
    inflammation, but all you're
    doing is covering up symptoms
    of a greater plight. Trans fats are
    like the devil of food, and chronic,
    systematic inflammation is
    possibly the number one culprit
    of all the preventable diseases
    that plague  humans, including
    arthritis, cancer and heart
    disease. If humans could just
    figure out how to balance their
    omega-6s and -3s, they could
    reduce and eliminate
    inflammation.

    How much do you know about
    grape seed oil production?


    Hexane is a hydrocarbon and a
    significant constituent of
    gasoline.
    Hexanes are colorless liquids at
    room temperature with a
    gasoline-like odor. They are
    cheap, non-polar solvents often
    used in the formulation of glues
    for shoes, leather products,
    textile manufacturing, roofing
    and for cleansing and
    degreasing.
    Unfortunately, they are also
    used to extract cooking oils
    from seeds, and we ARE talking
    about grape seeds here. Hexane
    is chiefly obtained by refining
    crude oil and is used in
    laboratories for chemical
    reactions. Did you know that the
    mutation of human cells, also
    known as cancer, is a "chemical
    reaction"?

    How much do you know about
    fake olive oil hybrids?


    More than HALF of all olive oil
    sold in the U.S. right now is not
    pure olive oil, or even "extra
    virgin" or "Italian." Many U.S. oils
    sold as such are hybrid mixes of
    toxic rapeseed oil (reduced
    erucic acid canola), GM soybean
    oil and other low-grade oils.
    Your body, if consuming these
    regularly, is breaking down like
    a car running on dirty oil and
    sugar-laden gasoline. Welcome
    to the scandalous world of fake
    olive oil! Real olive oil smells like
    fresh olives, because it's a fruit
    and hasn't been processed in
    labs and factories with chemicals.

    What is rapeseed oil?

    Over 90% of canola oil is partially
    hydrogenated and genetically
    modified, in case you didn't
    already know. That means that
    you are eating pesticide!
    (https://draxe.com) Rapeseed
    oil was banned for consumption
    in the USA by the FDA back in
    1956.
    Then a Canadian scientist
    lessened the toxicity, renamed it
    something catchy, and here we
    are! Canadian oil low acid is the
    long name for the cell choker.
     "Anti-conspiracy theorists" hate
    finding this one out. They really
    love their canola.

    Canola oil can have detrimental
    effects on your health, and most
    "food bars" at restaurants and
    supermarkets are loaded with it
    in just about every potato salad,
    egg salad, tuna salad, chicken
    salad and every baked item,
    including desserts and salad
    dressings.

    Coconut oil is the
    King of Healthy Oil!


    Your refuge in all of this is
    coconut oil. I suggest you buy
    only organic. This is the answer
    to the low-grade oil catastrophe
    that has struck America and will
    continue to do chronic, collateral
    damage for years. Escape the
    madness of low-grade oil being
    substituted for food. It's time
    you put only "premium fuel" in
    your "machine"!

    Sources for this article include:

    https://authoritynutrition.com

    https://www.naturalnews.com

    https://www.naturalnews.com




    Top food products 

    containing high-fructose

    corn syrup tainted with 

    mercury


    Ethan A. Huff
    @naturalnews.com

    (NaturalNews) Nearly half of all
    commercial high-fructose corn
    syrup
    (HFCS) used in processed
    foods like soda pop, ketchup
    and candy is tainted with toxic
    mercury, according to a peer-
    reviewed study published in the
    journal Environmental Health.
    Among 20 samples of
    commercial HFCS tested for the
    heavy metal, nine tested positive,
    says the Institute for Agriculture
    and Trade Policy (IATP), the
    consumer group that
    spearheaded the study.

    Researchers from IATP tested
    HFCS as part of a larger
    investigation into the safety of
    this common sweetener, which
    is often used in place of table
    sugar. Since it is used in
    everything from salad dressing
    and barbecue sauce to
    commercially prepared breads
    and cereals, HFCS is a major
    component of billions of people's
    diets, having been quietly
    introduced into the U.S. food
    supply during the 1980s.

    According to The Washington
    Post
    (WP), the average American
    consumes roughly 12
    tablespoons of HFCS daily, while
    teenagers and other "high
    consumers" are believed to
    consume up to 80 percent more,
    or roughly 22 tablespoons, of
    the substance every single day.
    Based on the findings of the
    study, this means that mercury is
    being ingested at levels never
    before seen, presenting serious
    health risks that could cause
    permanent health damage.

    "Mercury is toxic in all its forms,"
    stated Dr. David Wallinga from
    IATP, co-author of the study.
    "Given how much high-fructose
    corn syrup is consumed by
    children, it could be a significant
    additional source of mercury
    never before considered. We are
     calling for immediate changes
    by industry and the [U.S. Food
    and Drug Administration] to help
    stop this avoidable mercury
    contamination of the food
    supply."

    More than 30 percent of
    processed foods containing
    HFCS also contain toxic mercury

    IATP also conducted a joint
    study on individual consumer
    products containing HFCS,
    revealing that about one-third of
    them contain mercury. The most
    common products containing
    mercury were dairy products,
    dressings and condiments such
    as ketchup that contain HFCS as
    their first or second ingredients.

    A list of the 55 consumer
    products tested as part of the
    second study shows that the
    worst offender is Quaker
    Oatmeal to Go, which contained
    350 parts per trillion (ppt) of
    mercury. Second on the list is
    Jack Daniel's Barbecue Sauce,
    manufactured by Heinz, at 300
    ppt of mercury. Trailing these are
    Hershey's Chocolate Syrup at
    257 ppt of mercury, Kraft
    Original Barbecue Sauce at 200
    ppt of mercury and Nutri-Grain
    Strawberry Cereal Bars at 180
    ppt of mercury.

    The complete list of HFCS-
    containing products that tested
    positive for mercury can be
    downloaded as a PDF here:
    Iowa.SierraClub.org.

    Some HFCS producers using
    outdated 'mercury-cell'
    technology that poisons end
    product

    The reason why some HFCS
    contains mercury and other
    HFCS doesn't has to do with how
    the sugary product is
    manufactured. IATP told the
    Minneapolis Star Tribune that
    four HFCS plants in Georgia,
    Tennessee, Ohio and West
    Virginia still used a technology
    known as "mercury-cell" that can
    contaminate the end product.

    According to IATP, the process
    involves adding mercury-grade
    caustic soda, as well as other
    ingredients, to a proprietary mix
    that ultimately separates corn
    starch from corn kernels. This
    mercury-tainted caustic soda is
    manufactured in industrial
    chlorine plants that use an
    outdated and highly toxic chlor-
    alkali process that can leave
    mercury residue in the final
    product.

    "The bad news is that nobody
    knows whether or not their soda
    or snack food contains HFCS
    made from ingredients like
    caustic soda contaminated with
    mercury," added Dr. Wallinga.
    "The good news is that mercury
    -free HFCS ingredients exist.
    Food companies just need a
    good push to only use those
    ingredients."



    Are tanning beds and 

    the sun our enemy?


    Dr. Holick weighs in:



    Many doctors say ultraviolet light
    from the sun or a tanning
    machine is dangerous because
    of the risks associated with skin
    cancer. But some health experts,
    such as Dr. Michael Holick of
    Boston University, disagree. "I
    believe that Americans have
    gone overboard with their fear
    of the sun. I think that sensible
    exposure to sunlight is really
    important for your overall
    health and well-being," says
    Holick.

    The reason for the concern is
    vitamin D, essential for bone
    strength and other health needs,
    which our skin makes through
    exposure to the sun's ultraviolet
    rays. We need 1,000 units of
    vitamin D a day, but a glass of
    milk supplies only 100 units and
    a multivitamin only 400. So most
    people need the sun in order to
    avoid deficiency. Sunscreens can
    reduce vitamin D production Now,
    new research has found that
    wearing sunscreen continuously
    can reduce the amount of
    vitamin D a person is able to
    make.

    "We looked at individuals that
    always wore a sunscreen before
    they went outside. ... And we
    found that, indeed at the end of
    the summer, they were deficient
    in vitamin D," says Holick. "And
    so we have shown over and
    over again that adults, even if
    they're on a multivitamin, and
    drinking milk, if they always
    wear sun protection, or avoid
    any direct sun exposure,
    they're at high risk of
    developing vitamin D
    deficiency."

    Link Already Known,
    But Gaps in Knowledge


    Previous studies have shown a
    link between vitamin D levels
    and cancer risk and survival.
    Some studies have suggested
    that vitamin D levels are linked
    to colon cancer risk and an
    overall improvement in survival
    for a number of cancer types,
    including colorectal.

    An "umbrella review" Dr.
    Theodoratou was involved in
    found that using vitamin D for
    colorectal cancer prevention,
    and possibly treatment, is
    "biologically plausible" ,
    according to David J. Kerr, CBE,
    MD, DSc, professor of cancer
    medicine at the Oxford Cancer
    Centre in the United Kingdom.
    "Vitamin D has important effects
    on cell growth, cell morphology,
    and cell cytokinetics - a whole
    range of biological factors that
    would be relevant and germane
    to the control of cancer," he
    explained in a recent Kerr on
    Oncology.

    In their umbrella review, Dr.
    Theodoratou and colleagues
    note that "despite biological
    plausibility and a positive trend
    toward improvements in
    outcomes, in terms of
    prevention and in terms of
    reducing elements of disease
    recurrence, there were
    insufficient prospective
    randomized trials," Dr. Kerr
    pointed out.

    "There is a key gap in the
    knowledge - the defining
    evidence, the 'home run' if you
    like - that we would require to
    be utterly convinced of the role
    that vitamin D plays in the
    prevention and treatment of
    colorectal cancer," he said. 



    The role and benefits 

    of friendly bacteria 

    and how to use them 

    effectively


    (NaturalNews) Inside the body
    lives a vast number of bacteria
    without which we could not
    remain in good health. There
    are over 100 trillion bacteria in
    each person with over 400
    different species, most of them
    living in the digestive tract.
    Certain types of these bacteria
    help to maintain good health
    and others have value in
    regaining it back once it is lost.
    Learn the role and benefits of
    each, and when to use them.

    The role of different strains of
    friendly bacteria

    Lactobacillus acidophilus is the
    predominant friendly bacteria
    in the upper intestinal tract. It
    helps reduce the levels of
    harmful bacteria and yeasts in
    the small intestine and also
    produces lactase, an enzyme
    important in the digestion of
    milk. Acidophilus is involved in
    the production of B vitamins
    during the digestive process.

    Bifidobacterium bifidum and
    B. longum are the primary
    friendly bacteria in the large
    intestine. Bifidobacteria protect
    the large intestine from
    invading bacteria and yeasts,
    and also manufacture B
    vitamins and help the body
    detoxify bile. B. infantis is the
    prevalent friendly bacteria in the
    intestines of infants.

    Streptococcus thermophiles and
    L. bulgaricus are most
    commonly found in yogurt and
    exist only transiently in the
    digestive tract. They produce
    lactic acid, which encourages
    the growth of other friendly
    bacteria, and they also
    synthesize bacteriocins (natural
    antibiotics like substances) that
    kill harmful bacteria.

    Lactobacilli, Bifidobacteria, and
    Streptococci are the bacteria
    mostly commonly found in
    probiotic supplements. Other
    beneficial species that may be
    included are L. casei, L.
    plantarum, L. sporegenes, L.
    brevis, and saccharomyces
    boulardii. Without bacteria like
    acidophilus, one would not be
    able to properly digest food and
    absorb vitamins and other
    nutrients.

    The benefits of probiotics and
    illnesses they can help treat

    Probiotics can benefit our health
    in a number of different ways,
    including:

  • The manufacture of certain B 
  • vitamins, including niacin, 
  • pyridoxine, folic acid, and biotin.
  • Enhanced immune system 
  • activity.
  • Manufacture of milk-digesting 
  • enzyme lactase, which helps 
  • digest calcium rich dairy 
  • products.
  • Production of antibacterial 
  • substances that kill or 
  • deactivate hostile disease 
  • causing bacteria. Friendly 
  • bacteria do this by changing 
  • the local levels of acidity, by 
  • depriving pathogenic bacteria 
  • of their nutrients, or by 
  • actually producing their own 
  • antibiotic substances.
  • Anti-carcinogenic effect, 
  • since probiotics are active 
  • against certain tumours.
  • Improved efficiency of the 
  • digestive tract.
  • Reduction of high cholesterol 
  • levels.
  • Protection against radiation 
  • damage and deactivation of 
  • many toxic pollutants.
  • Recycling of estrogen, which 
  • reduces the likelihood of 
  • menopausal symptoms and 
  • osteoporosis.
  • Reduce anxiety and stress.


    Friendly bacteria have also been 
  • shown to be useful in 
  • treatment of acne, psoriasis, 
  • eczema, migraines, gout, 
  • rheumatic and arthritic 
  • conditions, cystitis, 
  • candidiasis, colitis, 
  • irritable bowel syndrome, 
  • and some forms of cancer.

    Using probiotics in specific 
  • situation.
  • Probiotics should always be 
  • considered a part of a healthy 
  • lifestyle due to its disease 
  • preventative properties, but 
  • could also be used in more 
  • acute and specific health 
  • challenging situations, such as:

  • Chronic bowel problems or 
  • infections
  • Food poisoning 
  • (bifidobacteria and 
  • acidophilus kill most food 
  • poisoning bacteria)
  • After antibiotics are taken
  • Premenopausal and 
  • menopausal women to 
  • reduce chances of 
  • osteoporosis.
  • High cholesterol problems
  • Radiation treatments
  • Vaginal or bladder infections 
  • (thrush or cystitis)


    Quality sources of probiotics

    Instead of immediately reaching 
  • for the probiotic capsules, 
  • also consider live food-based 
  • sources as the basis to a 
  • probiotic rich diet. Some of 
  • the most prolific sources 
  • include sauerkraut, kefir, 
  • kombucha, and apple cider 
  • vinegar.

    ** When you do reach for the 
  • probiotic capsules to 
  • combine with your better 
  • diet choices, be sure you 
  • have the right one! 



    Omega-3 supplements improve joint health, lessen severity of osteoarthritis and provide a host of other health benefits



    (NaturalNews) Omega-3 fatty acids may improve joint health and reduce the risk and severity of arthritis, according to a study conducted by researchers from Duke University and published in the Annals of the Rheumatic Diseases on July 11.

    The findings suggest that, contrary to prior belief, the types of fats that make up a person's diet may have more influence on their arthritis risk than their weight does.

    "Our results suggest that dietary factors play a more significant role than mechanical factors in the link between obesity and osteoarthritis," senior author Farshid Guilak, PhD, said.

    What you eat, not what you weigh

    Prior studies have established that obesity is a major risk factor for osteoarthritis, a disorder characterized by degradation of the joints and more commonly known simply as "arthritis." Until now, scientists have assumed that a higher body weight causes increased wear-and-tear on the joints, but this hypothesis never explained why arthritis is so common in non-weight-bearing parts of the body such as the hands.

    In a previous study, the Duke University researchers found that abnormally low levels of the appetite-regulating hormone leptin in obese mice were an accurate predictor of arthritis. This suggested that metabolic, rather than physical, symptoms of obesity might actually be behind arthritis.

    "This made us think that maybe it's not how much weight you gain, but what you eat," Guilak said.

    To further explore the connection between diet and arthritis, the researchers induced osteoarthritis in mice by deliberately injuring their knees. Trauma or injury is responsible for approximately 10 to 15 percent of all osteoarthritis cases. The arthritic mice were then fed either a diet high in saturated fat, a diet high in omega-6 fatty acids or a diet high in omega-6 fatty acids with a small amount of added omega-3s.

    "A healthy diet would include roughly equal ratios of these fats, but we're way off the scale in the Western diet," Guilak said.

    Health researchers now believe that the typical Western diet contains too much saturated and omega-6 fat, and not enough of omega-3 fat.

    Omega-3s slow disease progression, speed wound healing

    The researchers found no connection between body weight and arthritis. They did find that, while mice on both the saturated fat and omega-6 diets experienced a worsening of their arthritis symptoms over time, mice in the omega-6 plus omega-3 group did not.

    "While omega 3 fatty acids aren't reversing the injury, they appear to slow the progression of arthritis in this group of mice," Guilak said. "In fact, omega 3 fatty acids eliminated the detrimental effects of obesity in obese mice."

    The researchers also noticed that mice in the omega-3 group healed faster from an injury that the researchers had inflicted on their ears (a way to differentiate between the mice) than the mice in the other two groups.

    "We found that independent of body weight, dietary fatty acids regulate ear wound healing and severity of osteoarthritis following joint injury in obese mice," lead author Chia-Lung Wu said.

    The study was funded by the National Institutes of Health, the Arthritis Foundation, the North Carolina Biotechnology Center and a Taiwan GSSA graduate fellowship. It is only the latest in a glut of recent research illuminating the many health benefits of a diet high in omega-3 fatty acids.

    A strong body of clinical research now shows that omega-3s are potent anti-inflammatories that can reduce the risk of cardiovascular disease and arthritis. They are also important for brain health and particularly important for the brain development of babies and children. They may also play a role in regulating mood and cognitive function.

    Research has also linked omega-3s to a reduced risk of cancer and improved bone, bowel and menstrual health. [back to the top]



    Krill Oil Supplementation Lowers Your Triglycerides



    By Dr. Mercola

    Most Americans are seriously deficient in animal-based omega-3 fats. If you're among them, this means you are missing out on many health advantages that these fats offer.

    Maintaining a high dietary omega-3 intake throughout your life is essential for optimal health, and the research continues to pour in that krill oil, in particular, is the preferable source.

    Lower Your Triglycerides: Krill Oil for Your Heart

    Triglycerides are a type of fat in your blood. Elevated levels are linked to an increased risk of heart disease, and high triglycerides are also one of the signs of metabolic syndrome.

    Eating a healthful diet is one of the best ways to keep your triglyceride levels in the optimal range, and this includes omega-3 fats. Recent research published in Nutrition Research1 revealed that krill oil supplementation lowers triglyceride levels in adults with borderline high or high triglycerides - by more than 10 percent.

    The researchers concluded: "krill oil is effective in reducing a cardiovascular risk factor." This isn't the first time krill oil has been shown to reduce triglycerides, and past research also showed that it is more effective than fish oil at doing so.

    One study revealed that while the metabolic effects of the two oils are "essentially similar," krill oil is as effective as fish oil despite the fact that it contains less EPA and DHA (the primary active fatty acids in animal-based omega-3 fats).2

    In that case, the EPA and DHA dose in the krill oil was nearly 63 percent less than that in the fish oil - but the beneficial effects were virtually the same. This finding corresponds with unpublished data suggesting that krill oil is absorbed up to 10-15 times as well as fish oil, which would explain this discrepancy.

    Krill Oil Works Better Than Fish Oil, and on Par with Statins, to Improve Lipid Profiles

    Separate research published in the Journal of Animal Physiology and Animal Nutrition3 compared the efficiency of krill oil and fish oil in reducing triglyceride levels. Over a six-week period, rats divided into three groups had their diets supplemented with one of the following:

  • 2.5 percent krill oil
  • 2.5 percent fish oil
  • No supplement


    In less than three weeks, both oils had markedly reduced the enzyme activity that causes the liver to metabolize fat, but the krill oil had a far more pronounced effect, reducing liver triglycerides significantly more. The higher potency of krill oil allows it to decrease triglyceride levels in a shorter period of time compared to fish oil.

    Overall, after six weeks of supplementation, cholesterol levels in the krill oil group declined by 33 percent, compared to 21 percent in the fish oil group.

    Further, liver triglycerides were reduced by TWICE as much in the krill oil group compared to the fish oil group, by 20 percent and 10 percent, respectively. This is particularly important, as fasting triglyceride levels are a powerful indication of your body's ability to have healthy lipid profiles.

    To put this into further context, after being on a statin drug combined with daily exercise for several months, participants in one 1997 study4 saw an average reduction in their cholesterol levels of 20 percent. This is why krill oil is actually being used as a drug in some European countries.

    Krill Oil Is Less Damaged or Oxidized Than Fish Oil

    In laboratory tests, krill oil remained undamaged after being exposed to a steady flow of oxygen for 190 hours. Compare that to fish oil, which went rancid after just one hour. That makes krill oil nearly 200 times more resistant to oxidative damage compared to fish oil!

    When purchasing krill oil, you'll want to read the label and check the amount of astaxanthin it contains. The more the better, but anything above 0.2 mg per gram of krill oil will protect it from rancidity. To learn more about the benefits of krill versus fish oil, please see my interview with Dr. Rudi Moerck, a drug industry insider and an expert on omega-3 fats, above. The infographic below also presents the facts of which omega-3 supplement is best.

    I was one of the first to promote krill as an exceptional source of animal-based omega-3 dietary fats. Many have criticized me for recommending this over fish oil, for the lack of studies to back it up, but the bulk of the new emerging studies are confirming that krill is the better option.

    It merely took time for the science to document what was obvious clinically, that krill had the identical fats as fish oil but was a far higher quality source due to astaxanthin protecting the perishable fats, and the phospholipids that massively increase the absorption of the fats. [back to the top]



    3 common ways nutrients are being destroyed in your food



    (NaturalNews) One of the greatest concerns with the food supply today is the toxicity and lack of nutrients. This begins with the seed, then the soil it is planted in, followed by the treatment it receives during its growth phase. But if that wasn't enough, a further degradation of food takes place between the harvest and the plate. These are the three most prominent ways.

    Processing

    The most commonly eaten and most processed food category is arguably the grains. They often undergo a process that leaves them with a fraction of the nutritional value than when they were initially harvested in order to produce many types of flour products.

    To begin this process, the highly nutritious, sprout-able bran and the husk that has the fiber are removed leaving only the light yellow endosperm, which is virtually all starch with very little nutritional value and a high glycemic index rating.

    Following that, in order to bypass the aging process and add shelf life, as well as keep the clean white color, the endosperm is crushed and treated with chlorides to make it instantly white. A byproduct of that process is alloxan, which is used to induce diabetes in lab animals for medical testing.

    What is left is a food that has a mere remnant of its original nutrient value.

    Heating

    Another way the nutrients in food are destroyed is through heating. Various phytonutrients, enzymes, probiotics, and vitamins do no survive the heating process, which depletes the food of these life-promoting nutrients.

    One heating process that takes place prior to food making it to the store is pasteurization. This is commonly done with dairy products in order to remove any rogue bacteria that may be present during the harvesting process. Unfortunately, once it is pasteurized, it has removed all delicate and beneficial nutrients like enzymes and good bacteria, which are crucial for proper digestion and health.

    Another very common practice is cooking foods in ovens and on stovetops at high temperatures for extended periods of time, which results in the destruction of various nutrients.

    Finally, microwaving is the worst way to cook food because they excite the water molecules inside whatever you are cooking, causing heat to be formed from the inside out. This results in a cell-by-cell nuking of the food causing near-total molecular decomposition of the vitamins and phytonutrients that promote disease. This leaves microwaved food almost completely dead, leaving nothing but empty calories, fiber, and minerals. Virtually every vitamin and phytonutrient content has been destroyed.

    Irradiation

    This process exposes food to radioactive materials, such as cesium-137 and cobalt-60, to kill insects, bacteria, molds, and fungi, prevent sprouting, and extend shelf life.

    Unfortunately, foods that have been irradiated lose much of their nutritional value. Irradiation can destroy between 5 and 80 percent of vitamins and nutrients found in a variety of foods including essential vitamins A, B complex, C, E, and K. As an example, irradiated eggs lose 80 percent of vitamin A and orange juice loses 48 percent of beta-carotene.

    Although the heating and irradiation process are often done by governmental organizations to reduce the number of food borne illnesses, it has indirectly created a policy that increases the number of people killed by infections and chronic disease due to destruction of probiotics, enzymes, and other nutrients that help the body resist and destroy infection in the body.

    The bottom line is that the more whole, raw, and fresh the food consumed, the healthier the immune and detoxification systems that destroy such harmful pathogens. [back to the top]



    New Evidence for Protective Effects of Vitamin-D on Your Heart



    By Paolo Boffetta, MD, MPH, Special to Everyday Health

    Although vitamin D is obtained from diet and dietary supplements, the main source of vitamin D is production in our skin under the influence of solar radiation.

    As sun exposure varies with the latitude of regions and during the year, so vitamin D concentrations of populations vary accordingly. Furthermore, women are generally more prone to low vitamin D concentrations than men. Vitamin D deficiency is especially common among the elderly who often have less sun exposure because of reduced outdoor activity and reduced capacity of the skin to produce vitamin D.

    Research on Vitamin D's Protective Role

    We conducted an international study of eight populations from Europe and the United States to investigate the association of level of vitamin D in blood and deaths from all-causes, cardiovascular diseases, and cancer mortality, published in the British Medical Journal in June 2014. We paid attention to differences between countries, sexes, age groups and seasons of blood sampling. The study was conducted with the CHANCES Project, a research initiative funded by the European Commission and coordinated by scientists at the Hellenic Health Foundation in Athens, Greece, and Mount Sinai School of Medicine in New York, and primary authors were from the German Cancer Research Center, in Heidelberg.

    A total of 26,018 people had their vitamin D level measured in blood samples collected at enrolment in the study, when they were ages 50 to 79, and were followed for an average of 4 to 16 years, depending on the population. During this period 6,695 of them died, including 2,624 from cardiovascular disease and 2,227 from cancer. We compared the risk of dying between the group with highest vitamin D level and those with lower levels by dividing each study population in five groups of equal size based on their baseline vitamin D level.

    Increased Deaths in People With Low Vitamin D Levels

    Compared with the group with the highest vitamin D, people in the group with lowest vitamin D had a 57 percent increased mortality for all causes. They also had a 41 percent increased mortality from heart disease for those who were free from heart disease at the study's start. In addition, individuals with history of cardiovascular disease had a 65 percent increased risk. People with a history of cancer had a 70 percent increased risk. However, for cancer mortality, we saw no benefit in those who were free from cancer at the start.

    For all these associations, the three groups with intermediate vitamin D level were at intermediate risk, with a dose-response relation. These associations did not vary by sex, age group, or season of blood collection.

    For the US population in the study, the comparison was between people with level of 25-hydroxyvitamin D (the main metabolite of vitamin D, and the active compound measured in blood) just above 85 nmol/L on the high end, and people with a level below about 42 nmol/L on the lowest. In that population, the difference in mortality was 42 percent for all causes and 26 percent for cardiovascular diseases.

    Since ours an observational study, it cannot directly address the issue of causality. In other words, it is possible that blood vitamin D is a marker of some other characteristics causally linked to disease and mortality, like general good or poor health status. Controlled vitamin D trials, in which individuals are randomly allocated to vitamin D supplement or placebo, are needed to disentangle the effect of vitamin D from that of other factors. However, such studies can only address the effect of dietary supplementation, not of normal dietary intake and sun-related endogenous production. Prior trials showed a protective effect of vitamin D on mortality, albeit of smaller magnitude than observational studies, including ours.

    Why Vitamin D Is Good for the Heart

    If indeed the protective effect of vitamin D on mortality is real, our study provides important evidence that the effect is present for cardiovascular disease - but not for cancer. The protective effect is present at all ages and in both sexes. Unfortunately, our study did not include a sufficient number of people of different racial and ethnic groups to provide information on this important issue.

    An important question is the identification of who should increase their vitamin D status using supplements. There is no consensus on ideal cut-off values for vitamin D deficiency. Our observation that the use of cut-off levels which were specific for country, age, sex, or season produced comparable results, raises the question whether such factors should be considered for defining vitamin D deficiency.

    Future population-based studies with standardized vitamin D measurements are needed to fully resolve this issue; in the meantime, caution should be used in extrapolating results across regions with different latitudes.

    Despite these uncertainties, I recommend moderate sun exposure, in particular in the elderly. The amount of sun exposure depends on the type of skin (15-30 minutes are sufficient for a fair skinned person, while one or two hours are needed for dark skinned person) and on the latitude the person lives (more time is needed in Northern regions, in particular in winter). If sun exposure is not sufficient, people can consider taking supplements, after talking with their doctor.

    Paolo Boffetta, MD, MPH is a chronic disease epidemiologist who is Director of the Institute for Translational Epidemiology and Associate Director for Population Sciences of the Tisch Cancer Institute at the Icahn School of Medicine, which is part of Mount Sinai Medical Center in New York City. He is also Adjunct Professor in the Department of Medicine at Vanderbilt University in Nashville, Tenn., and in the Department of Epidemiology at the Harvard School of Public Health. He has edited 12 books and published more than 1,000 peer-reviewed scientific articles. [back to the top]



    Vitamin D Deficiency Linked to Schizophrenia



    Deborah Brauser -- July 29, 2014 -- Dr. Ahmad Esmaillzadeh

    A review of 19 studies, which included more than 2800 participants, showed that those with vitamin D deficiency were more than twice as likely to be diagnosed with schizophrenia compared with their counterparts who were not vitamin D deficient.

    In addition, 65% of the patients who had schizophrenia also had lower levels of vitamin D.

    Coinvestigator Ahmad Esmaillzadeh, PhD, associate professor in the Department of Community Nutrition in the School of Nutrition and Food Science at the Isfahan University of Medical Sciences in Iran, told Medscape Medical News that although lower levels of serum vitamin D were expected in these patients because of earlier ecologic and epidemiologic studies, "we were surprised by the significant 2.16 times increased risk of schizophrenia in vitamin D deficient individuals. We did not expect such a significant increase," he added.

    Dr. Esmailzadeh noted that the findings support the importance of vitamin D in brain function and psychological health.

    "As vitamin D deficiency is a global issue, more attention should be drawn to assessment of serum vitamin D levels in order to screen and support individuals that are at higher risk of having deficiencies. Moreover, our findings might help psychiatrists in the healing process of patients with schizophrenia," he said.

    "However, controlled clinical trials are needed to confirm the effects of vitamin D supplementation," he added.

    The study was published online July 22 in the Journal of Clinical Endocrinology and Metabolism.

    Global Issue

    Dr. Esmailladeh noted that vitamin D deficiency is "relatively prevalent" globally and is associated with several disorders. For instance, previous studies have reported a link between these lower levels and depression.

    "We were interested in the role of vitamin D in psychiatric health and, due to conflicting data on the association between serum levels of vitamin D and schizophrenia and no comprehensive meta-analysis in this regard, we aimed to conduct this study," he added.

    The investigators examined data from 19 studies, published between 1988 and 2013, that assessed serum vitamin D levels in adult patients with schizophrenia. They then conducted 3 separate meta-analyses.

    The number of patients in each study ranged from 17 to 848, for a total of 2804. In addition, 11 of the studies were conducted in European countries, and 8 were conducted in non-European countries.

    The first meta-analysis included 13 of the studies and examined mean levels of 25-hydroxyvitamin D. The second included 8 studies and examined vitamin D deficiency prevalence; and the third included 8 studies and focused on odds ratios.

    Some of the studies were included in overlapping meta-analyses.

    Suspicions Confirmed

    "For the most part, this confirms what we've long been expecting, based on all of the other epidemiologic data out there," Michael F. Holick, MD, PhD, from the Department of Medicine; the Section of Endocrinology, Nutrition, and Diabetes; and the Vitamin D, Skin, and Bone Research Laboratory at Boston University Medical Center in Massachusetts, told Medscape Medical News.

    Dr. Michael Holick

    The investigators "took into account sunlight exposure and a whole variety of variables and concluded that schizophrenic patients are more likely to be vitamin D deficient. And that is consistent with the concept that vitamin D deficiency is associated with increased risk for schizophrenia," said Dr. Holick, who was not involved with this research.

    He noted that approximately 30% of children and adults around the world are vitamin D deficient - and 60% are deficient or insufficient.

    "So we recommend vitamin D supplementation across the board. The Endocrine Society recommends for children 1 year and older, 600 to 1000 units a day; for adults, 800 to 2000 units a day; and for people who are overweight or obese, they need 2 to 3 times more to both treat and satisfy their deficiency," he said.

    Dr. Holick noted that both the Institute of Medicine and the Endocrine Society do not have specific recommendations for this type of supplementation in pregnant women. However, he recommends 2000 units per day along with other dietary sources of vitamin D, such as milk, and normal prenatal vitamins.

    "We know from a study recently done in South Carolina that pregnant women taking 4000 units of vitamin D a day had robust, healthy levels of 25-hydroxyvitamin D and no untoward toxicity. So 4000 units were easily tolerated and may be preferred by pregnant women," he said.

    He added that although it may not be possible to prevent schizophrenia, there is hope to decrease the risk for the disorder.

    "The [current] investigators conclude, which is consistent with a lot of literature, that there is a 2-fold higher risk of having schizophrenia based on being vitamin D deficient. And I think that is the major message," he said.

    "Vitamin D deficiency is extremely common in this population. Therefore, physicians caring for these patients should be aggressive in treating the deficiency, and then they may actually improve how [patients] respond to their medication, making them feel better as their mood improves, all for the benefit of their mental health." [back to the top]



    Gout in the elderly. Clinical presentation and treatment (Pubmed.gov)



    Abstract

    Gout in the elderly differs from classical gout found in middle-aged men in several respects: it has a more equal gender distribution, frequent polyarticular presentation with involvement of the joints of the upper extremities, fewer acute gouty episodes, a more indolent chronic clinical course, and an increased incidence of tophi. Long term diuretic use in patients with hypertension or congestive cardiac failure, renal insufficiency, prophylactic low dose aspirin (acetylsalicylic acid), and alcohol (ethanol) abuse (particularly by men) are factors associated with the development of hyperuricaemia and gout in the elderly. Extreme caution is necessary when prescribing nonsteroidal anti-inflammatory drugs (NSAIDs) for the treatment of acute gouty arthritis in the elderly. NSAIDs with short plasma half-life (such as diclofenac and ketoprofen) are preferred, but these drugs are not recommended in patients with peptic ulcer disease, renal failure, uncontrolled hypertension or cardiac failure. Colchicine is poorly tolerated in the elderly and is best avoided. Intra-articular and systemic corticosteroids are increasingly being used for treating acute gouty flares in aged patients with medical disorders contraindicating NSAID therapy. Urate-lowering drugs are indicated for the treatment of hyperuricaemia and chronic gouty arthritis. Uricosuric drugs are poorly tolerated and the frequent presence of renal impairment in the elderly renders these drugs ineffective. Allopurinol is the urate-lowering drug of choice, but its use in the aged is associated with an increased incidence of both cutaneous and severe hypersensitivity reactions. To minimise this risk, allopurinol dose must be kept low. A starting dose of allopurinal 50 to 100mg on alternate days, to a maximum daily dose of about 100 to 300mg, based upon the patient's creatinine clearance and serum urate level, is recommended. Asymptomatic hyperuricaemia is not an indication for long term urate-lowering therapy; the risks of drug toxicity often outweigh any benefit. [back to the top]




    Risk of heart attack and stroke doubles for patients with gout (MNT)



    New research published in Rheumatology journal has found that having gout doubles the risk of heart attack and stroke. The research tracked the health of more than 205,000 gout patients using data spanning five decades to determine links between gout and heart attack and stroke.

    The findings showed that gout patients are twice as likely to suffer a heart attack or stroke as those without gout. It is thought that the higher levels of uric acid which cause gout are also a strong risk factor for heart attack and stroke.

    Conducted by scientists at the University of Oxford, the research used data from NHS England and the Office for National Statistics. Two sets of data for gout patients between 1963 and 2011 were used to track patients' health and to determine the link between gout and heart attack and stroke in England.

    These new findings highlight the need to address co-morbidities and include preventative measures within gout treatment to reduce heart attacks and stroke in gout patients.

    Professor Rob Moots, editor of Rheumatology, said:

    "This important study tells us that gout is a condition that is more than just a cause of severe pain, it is rather disease that must be taken seriously and treated effectively to prevent unnecessary heart attacks and strokes."

    Dr Chris Deighton, president of the British Society for Rheumatology, said:

    "This research reminds us that gout needs to be considered in a much broader context than just inflammatory arthritis. The vast majority of care for gout takes place in primary care. GPs need to know that gout is not only a highly curable form of arthritis, but these patients also need vigilance for their increased risk of heart attacks and strokes. High quality holistic care of people with gout may not only improve their quality of life, but also the quantity of years lived."

    Olena Seminog, lead researcher, said:

    "By analysing a huge dataset spanning a long period of time for all of England our group found that gout patients have double the risk of myocardial infarction and stroke. This evidence could help to guide ways of improving cardiovascular health for people with gout, while also suggesting that more research is needed to reveal the effects of uric acid on our health." [back to the top]




    Are There Other Options Besides Medications for Gout and Osteoarthritis? (Julie Chen, M.D.- Integrative Medical Doctor)



    Most of my patients in my integrative medicine clinic in San Jose, California know that one of my personal passions is the treatment of rheumatological diseases. It definitely helps that these diseases respond very well to diet and lifestyle changes (3,4), but more importantly, the honor of being able to witness significant improvement in quality of life for these patients after they make these changes is very rewarding to say the least.

    Due the strong impact of diet and nutritional intake and many various diseases (3,4), I would like to spend the next couple of months discussing various dietary changes that have been seen to be helpful with various types of rheumatological conditions.

    This month, I would like to kick off this series with a focus on gout and osteoarthritis.

    Gout is a defect in intermediate breakdown that leads to uric acid build up (3,4). Foods rich in purines help with uric acid production and thus should be avoided in patients with gout (3,4). These foods include but are not limited to beer, organ meats, yeast, shellfish, sardines, herring, and bacon (3). Alcohol helps to increase purine production and lowers our kidney's ability to clear out uric acid (3,4) therefore high purine foods and alcohol consumption for those with gout is not recommended.

    Being overweight is associated with increased uric acid levels and gout flares (3). It seems that early studies suggest a diet that is low in carbohydrates and is restricted in calories with a large amount of monounsaturated fats and higher in total daily protein than previously recommended may be beneficial to patients with gout (3,4). When you look at all of this information together, a diet low in carbohydrate or sugar load and an emphasis on weight loss is indicative of gout status improvement (3).

    Osteoarthritis (OA) is a degenerative arthritis or, as my patients like to say, an arthritis from wear and tear of aging. This state can be accelerated by obesity and so weight management is important especially for osteoarthritis of the knee and hips (3,4). Therefore, it makes sense that weight loss is important in helping symptoms of osteoarthritis (3,4).

    Although many people may think that with joint pains, they should not exercise or work out, that is not true. Physical activity is beneficial for osteoarthritis simply because it helps to maintain mobility and helps with our weight management which directly helps to stem the negative impact of OA (3,4). If joint degeneration is severe and you are not able to easily exercise, some other options that are gentler on joints are swimming and qi gong (3,4).

    In terms of supplements, are there any that are beneficial to OA?

    Some studies suggest that antioxidants are helpful for OA and that having adequate vitamin D levels are known to help limit progression of OA (4). There are also some early observational evidence that certain vitamin deficiencies like vitamin D and K can negatively impact osteoarthritis joint status (3,4).

    Many people ask me about glucosamine sulfate as therapy for OA. The answer to that is that there is some evidence that it can help with mild to moderate OA so as to help limit disease progression but it is not great at giving immediate pain relief (5).

    So in regards to pain relief, if you don't want to use the typical prescription or over the counter pain medications, what should you use?

    Omega-3 fatty acids are a great choice for inflammatory joint symptoms. So I would recommend this for not just OA but also for gout (2). Our current modern diet has a higher preponderance of omega-6 to omega-3 ratio but our ancestors had diets that were more balanced between omega-6 and omega-3 fatty acids (2). The reason why we want a diet higher in omega-3 is that they lead to generation of anti-inflammatory chemicals called cytokines (2). Despite my noting of the fact that we need more omega-3, that doesn't mean we don't need omega-6, it's just that there should be a closer balance of the two rather than a large predominance of omega-6 over omega-3 (2). Other options for joint pain relief include the potential usage of capsaicin, ginger, and SAMe (1,6,7).

    Although I am a big proponent of herbal and vitamin therapy, I want to caution readers to always check with your physician before using any supplements. You should not think that just because it's not a prescription medication, everything over the counter is safe for everyone. So, my recommendation is to play it safe and always check with your physician before using any supplements and to let them know what you are taking so they can keep their list of your therapeutic regimen updated.

    So, in summary for the information we addressed this month for osteoarthritis and gout, the main takeaway points are that a diet that is more vegetable-based and healthy lean protein-based with lower carbohydrates can help with diseases like gout. But most importantly, a diet such as this were we are trying to prevent insulin resistance can help with inflammation as well as weight management. Obesity and being overweight are linked to higher disease state complications and progression of both gout and osteoarthritis. So getting yourself into target weight is important for joint health. (3.4)

    Finally, if you would prefer not to use over the counter or prescription medications, some supplement options were discussed but I would like to again make sure I am clear that I am a big proponent of you checking with your doctors first before starting any supplements. Just because something is a supplement, doesn't mean it is always safe... but similarly, just because it's a supplement, doesn't mean it won't work or it's just placebo effect because some studies suggest that various options we discussed can be therapeutic and helpful in gout and osteoarthritis. (1-7)

    References:

    1. Altman RD, et al. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum 2001;44:2531-2538.
    2. Calder PC. N-3 polyunsaturated fatty acids and cytokine production in health and disease. Ann Nutr Metab 1997;41:203.
    3. Cleland LG, et al. Diet and arthritis. Bailleres Clin Rheumatol 1995;9:771.
    4. Katz, DL. Nutrition in Clinical Practice 2nd Edition. 2008.Lippincott Williams and Wilkins. Philadelphia, PA.
    5. Pavelka K et al. Glucosamine sulfate use and delay of pregression of knee osteoarthritis: a 3-year randomized placebo-controlled dougle blind study. Arch Intern Med. 2002;162:2113-2123.
    6. Soeken KL, et al. Safety and efficacy of SAMe for osteoarthritis: a meta-analysis. J Fam Practice 2002;51:425-426.
    7. Zhang WY, et al. The effectiveness of topically applied capsaicin. A meta-analysis. Eur J Clin Pharmacol 1994;46:517-522. [back to the top]




    High Temperature, Low Humidity Associated With Gout Attacks? (By Anne Harding)



    NEW YORK (Reuters Health) - Recurrent gout attacks are twice as likely to strike on hot days when humidity is low, according to new findings.

    The risk of gout attacks was also increased under hot, humid conditions compared to moderate temperature and relative humidity, but to a lesser degree, Dr. Tuhina Neogi of Boston University School of Medicine and her colleagues found.

    "Our findings imply that high temperatures and low humidity in combination are risk factors for triggering gout attacks," Dr. Neogi told Reuters Health. "We think that probably reflects the fact that there is more evaporative loss when the temperature is high and there is low humidity."

    Based on the findings, she added, physicians should advise their patients with gout to stay well-hydrated with appropriate fluids - ideally, water - during hot weather.

    The study is the first to look at weather factors and the risk of recurrent gout attacks, the researchers note. They conducted an Internet-based case-crossover study of 632 patients who had experienced at least one gout attack in the 12 months before enrollment. Patients were followed from 2003 to 2010.

    The researchers used data from the National Oceanic and Atmospheric Administration to track weather conditions in each patient's zip code during the 48 hours leading up to gout attacks and during control periods.

    Higher temperatures during the previous 48 hours were positively associated with gout attack risk. Individuals were at 43% greater risk of an attack when temperatures were between 70 and 79 degrees Fahrenheit and at 40% greater risk with temperatures at 80 degrees and above, compared to when temperatures were between 50 and 59 degrees (p for linear trend = 0.01).

    There was a reverse J-shaped relationship between humidity and gout attack risk. When relative humidity was less than 40% over the past 48 hours, the likelihood of an attack was 55% higher than with relative humidity of 60% to 74%. At the other end of the spectrum, the risk was 14% higher for relative humidity of 75% to 84% and 11% higher for relative humidity of 85% or above.

    The greatest risk occurred when temperatures were 70 degrees or higher for the previous 48 hours and relative humidity was below 60%, with an odds ratio for attacks of 2.04 compared to when temperatures were in the 50s and 60s and humidity was 60% to 74%.

    The findings were published online July 3 in the American Journal of Epidemiology.

    When it's humid out, Dr. Neogi noted, people feel the sweat on their skin and recognize that they need to increase their fluid intake; when it's less humid, she added, they may not be as aware that they are at risk of fluid depletion.

    She and her colleagues conclude, "The biological mechanisms underlying these associations require further exploration and may include volume depletion or behavioral changes in response to the weather that may influence gout attack risk. Patients with gout may be advised that under conditions of hot and/or dry weather, appropriate measures, such as increased water intake, should be considered to minimize the risk of recurrent gout attacks."




    Nine Reasons Why You Should Eat Sweet Potatoes (NaturalNews)

    (NaturalNews) Sweet potatoes are packed with nutrition. They are a great source of minerals such as manganese, folate, copper, and iron. The darker-colored variety is a great source of carotenes (precursor of vitamin A), vitamins C, B2, B6, E and biotin. Sweet potatoes are also a fantastic source of dietary fiber. Here are nine reasons you should be eating more sweet potatoes:

    1. Sweet potatoes are high in antioxidants, which work in the body to prevent inflammatory problems like asthma, arthritis, gout, and many more.

    2. Sweet potatoes are an excellent source of carbohydrates for those with blood sugar problems. These fibrous root vegetables can help regulate blood sugar levels and prevent conditions like insulin resistance.

    3. Sweet potatoes are healthy for the digestive tract. Being rich in digestive fiber, especially when the skin is also consumed, it helps to relieve constipation and may prevent colon cancer.

    4. Sweet potatoes are good for those who are pregnant or trying to conceive because they are high in folate, which is essential for the healthy development of fetal cell and tissue.

    5. Packed with important vitamins and other nutrients, eating sweet potatoes can boost immunity by supporting the needs of the body.

    6. Sweet potatoes are good for preventing heart disease. High in potassium, sweet potatoes can help prevent the onset of heart attack and stroke. Potassium also helps to maintain fluid and electrolyte balance in the body, which is important for stabilizing blood pressure and regulating heart function.

    7. Sweet potatoes are good for alleviating muscle cramps. Potassium deficiencies are a leading cause of muscle cramps, as well injuries. By making sweet potatoes a regular part of your diet (along with proper exercise), you can expect an energy boost and fewer muscle cramps and injuries.

    8. Sweet potatoes are good for treating stress-related symptoms. The body tends to use a lot of potassium and other important minerals when it is under stress. Sweet potatoes provide important minerals that will help maintain balance throughout the body during times of stress.

    9. Sweet potatoes ranked number one in nutrition out of all vegetables by the Center for Science in the Public Interest because they are such a rich source of dietary fiber, natural sugars, complex carbohydrates, protein, carotenoids, vitamin C, iron and calcium.




    Quinoa's Many Health Benefits (NaturalNews)



    (NaturalNews) Quinoa is a grain crop native to the Andean Mountains of South America. Although the leaves of the plant can be consumed as a leaf vegetable, quinoa is primarily grown for its seeds. These seeds, which are cooked in a similar way to rice, come in three colors (red, white and black) and are much-loved for their significant health benefits. In fact, 2013 was crowned "The International Year of Quinoa" by the United Nations due to quinoa's high nutritional value and potential to contribute to global food security. (1)

    A complete protein source

    One of quinoa's biggest draws, particularly for vegetarians and vegans, is its considerable protein content. According to Self's "NutritionData," one cup of cooked quinoa contains 16 percent of our recommended daily allowance (RDA) of protein. (2) Moreover, this protein contains all eight essential amino acids, making quinoa a rare example of a plant-based complete protein source (most plant foods are deficient in some amino acids, such as lysine). Protein, of course, aids the growth and repair of cells, supplies energy to our bodies and much more.

    Packed with fiber

    One cup of cooked quinoa also contains a whopping 21 percent of our RDA of fiber, which is twice as much fiber as most other grains. (2) Most of quinoa's fiber is the insoluble kind that contains the well-known laxative effect, but it also contains smaller amounts of insoluble fiber that forms a gel in the stomach, thereby slowing digestion, encouraging a feeling of fullness, and reducing LDL cholesterol in the bloodstream. This well-rounded fiber profile gives quinoa a low glycemic load of 53, making it a suitable food for diabetics and pre-diabetics.

    High in antioxidants

    A study published in the Journal of Medicinal Food in August 2009 showed that of the 10 Andean grains analyzed by the researchers (five cereals, three pseudocereals and two legumes), quinoa contained the most antioxidants out of all of them. (3) Another 2009 study published in Food Chemistry showed that allowing quinoa seeds to sprout could increase their antioxidant content further. (4) Antioxidant-rich foods are well-known for their anti-aging properties and ability to prevent degenerative diseases such as cancer, rheumatoid arthritis, macular degeneration and Alzheimer's disease.

    Rich in quercetin and kaempferol

    Quinoa is an excellent source of the flavonoids quercetin and kaempferol, which are shown to possess anti-inflammatory, anti-viral and anti-cancer effects. A study published in Neuropharmacology in 2010 even found that flavonoids contained anti-depressant properties, suggesting that flavonoid-rich foods like quinoa could provide treatment for depression, anxiety and other low moods. (5)

    Gluten-free

    According to a survey published by The NPD Group in 2013, approximately one-third of the United States population are trying to minimize or avoid gluten due to health concerns. (6) Fortunately for this growing minority, quinoa is naturally gluten-free and is a safe food for those with gluten intolerance or celiac disease. Moreover, unlike many processed "gluten-free" foods, quinoa is a whole food that is free from additives and other undesirable ingredients.

    Bursting with nutrients

    Quinoa is an excellent source of essential nutrients such as calcium, iron, phosphorus, manganese, copper, selenium and most B vitamins. One cup of quinoa also supplies us with an impressive 30 percent of our RDA of magnesium, in which up to an estimated 80 percent of the American population are deficient. (2)

    Organic quinoa is easily found online or in health food stores. It only takes between 15 and 20 minutes to cook, has a pleasant, nutty flavor, and is easy to incorporate into both cooked and cold meals.




    Artificial Sweeteners Linked to Glucose Intolerance (Beth Skwarecki)



    September 17, 2014

    The artificial sweeteners aspartame, sucralose, and saccharin cause blood glucose abnormalities in mice and some humans, a team reports in an article published online September 17 in Nature. The changes in glucose tolerance seem to be driven by the microbiome and can be reproduced in germ-free mice by giving them gut microbes from a person who has consumed the sweeteners.

    "We found that artificial sweeteners may drive...an exaggerated elevation in blood glucose levels, the very same condition that we often aim to prevent by consuming them," Eran Elinav, MD, PhD, from the Department of Immunology at the Weizmann Institute of Science, Rehovot, Israel, said at a press briefing.

    The investigators began with experiments in mice, giving each animal 1 of 3 artificial sweeteners in its water: aspartame, sucralose, or saccharin. Because commercial preparations of these sweeteners also contain some glucose, researchers used glucose, fructose, or plain water for the control mice to ensure it was the artificial sweetener and not any added sugar that was responsible for the effect. "To our surprise, we found they all induced a blood sugar disturbance even compared to mice who drank sugary water," Dr. Elinav said. This effect occurred on both a normal diet of rat chow (P < .001) and a high-fat diet in which 60% of calories came from fat (P < .03).

    Because these artificial sweeteners are not digested or absorbed by the human body, the investigators hypothesized that gut microbes were responsible for the results. They administered antibiotics to the mice: 1 group received ciprofloxacin and metronidazole, a broad-spectrum approach focusing on gram-negative bacteria, and another group received vancomycin, aimed against gram-positive bacteria. Both treatments, when given for 4 weeks, eliminated the differences in glucose tolerance between sweetener-fed mice and controls.

    The symptoms could also be triggered by a microbial transplant. Microbes from mice who had been drinking saccharin were transplanted via feces into germ-free mice and caused the recipients to show impaired glucose tolerance, whereas microbes from mice who had been drinking glucose did not (P < .03). Further, to show that the microbes were responsible, and not some other component of the feces, the researchers cultured bacteria from mice who were not eating sweeteners and added saccharin to the growth media. These bacteria were then transplanted into germ-free mice, resulting in impaired glucose tolerance compared with mice that received a control culture (P < .002).

    Bacterial Profiles

    The researchers performed both 16S sequencing, to identify the bacteria that were over- or underrepresented in mice with impaired glucose tolerance, and metagenomic sequencing, to identify what those bacteria are doing. In the microbial ecosystems from mice that ate artificial sweeteners, the pathways that were overrepresented included several that had previously been linked to diabetes and glucose intolerance. Glycan degradation, for example, occurs when microbes digest certain chains of sugars and create short-chain fatty acids that the body can use for energy, providing extra calories. The investigators confirmed that the sweetener-fed mice had increased amounts of this end product, the short chain fatty acids, in their guts.

    In Humans

    Artificial sweeteners caused changes in glucose tolerance in humans, as well, but only for some participants the investigators consider to be "responders." A group of 7 healthy volunteers who do not normally consume artificial sweeteners were given saccharin for 6 days at a dose that met the US Food and Drug Administration's maximum acceptable daily intake of saccharin for humans. No participants saw improvements in glucose tolerance, but 4 showed impairment.

    Even before the experiment began, the microbial ecosystems from the 4 responders were different from those of the 3 nonresponders, suggesting their microbiome was somehow more susceptible. These results, said Dr. Elinav, "point to the personalized nature of our food responses and the need to understand this personalized effect in order to fight the metabolic syndrome, which as we all know, is one of the most common and serious epidemics in all history."

    Bacteria from responders, sampled at the end of the trial, were able to induce glucose intolerance when introduced into germ-free mice (P < .02), whereas baseline samples from the responders (taken before they had consumed the artificial sweeteners) did not have this effect, nor did bacteria from the nonresponders.

    Trend Seen With Long-Term Consumption

    A further experiment involving 381 nondiabetic participants showed that long-term consumption of artificial sweeteners was associated with measures of central obesity and glucose intolerance, even when corrected for body mass index.

    The authors caution that the results from the human experiments are not yet enough to make recommendations about whether or not people should consume sweeteners. They also point out that the mechanism for the sweeteners' effect is unknown: it may be causing less desirable bacteria to thrive, or it may be poisoning certain normal bacteria, allowing detrimental species to take their place.

    In an accompanying editorial, Taylor Feehley, BA, and Cathryn Nagler, PhD, both from the Department of Pathology at the University of Chicago, note that "Whether the bacterial populations or metabolic pathways altered by the consumption of [artificial sweeteners] are similar to those described in people with or developing diabetes remains to be seen."




    Study: Eating High-Fat Dairy Lowers Type 2 Diabetes Risk (todayhealthchannel.com)



    High-fat diets have been enjoying excellent press lately. Earlier this month a study was published showing that low-carb diets outperform low-fat diets for both weight loss and heart health. This week, a new study suggests that people eating high-fat dairy products are at significantly lower risk of developing Type 2 Diabetes than those eating less dairy.

    The study was presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria. It included data for nearly 27,000 people (60% women), aged 45-74 years, culled from the Swedish Malmo Diet and Cancer Study. Study participants were tracked for 14 years after original data collection, during which time 2,680 cases of Type 2 diabetes were diagnosed.

    The results showed that study participants eating eight portions of high-fat dairy a day (including cream and whole milk) had a 23% lower incidence of developing diabetes than those eating one portion a day. The same effect was not found for those eating low-fat dairy products.

    Researchers controlled for a range of factors to weed out other possible contributing causes, including total energy intake, BMI, leisure time physical activity, smoking, alcohol consumption and education.

    The study also tracked diabetes rates associated with eating meat and meat products like sausage, and found an increased risk of developing the disease for those eating the most meat, regardless of fat content. But, people eating lower-fat meats were at greater risk than those eating high-fat meats (9% greater risk for high-fat meats versus 24% for low-fat meats).

    The results suggest that when it comes to diabetes risk, not all fats are created equal. Dairy fats may actually provide protection against the disease.

    Quoting lead study author Dr. Ulrika Ericson, from the Lund University Diabetes Center in Malmo, Sweden: "Our observations may contribute to clarifying previous findings regarding dietary fats and their food sources in relation to Type 2 diabetes. The decreased risk at high intakes of high- fat dairy products, but not of low-fat dairy products, indicate that dairy fat, at least partly, explains observed protective associations between dairy intake and Type 2 diabetes."

    If you're wondering, "eight portions" of high-fat dairy in this study is the equivalent of about six ounces of whole milk or a little over one ounce of whole cream per day. That's about two and a half tablespoons of cream in a cup of coffee.

    Don't run out to raid the dairy aisle just yet. While this study included data from a large population sample, there are significant differences between the average American's diet and the average European's. Dairy appears to be a distinguishing factor in diabetes risk within the context of a typical Swedish diet, but we don't know if the results would hold true with a similarly sized U.S. population sample. Future research will have to plumb that possibility.

    At the very least, these results add to a growing list of findings suggesting that fat may not deserve the dietary arch villain label it has carried for decades.




    7 Reasons to Eat More Saturated Fat(Dr. Mercola)



    Tim Ferriss of The Four-Hour Work Week has posted an exclusive excerpt from Drs. Michael and Mary Eades' newest book, The 6-Week Cure for the Middle-Aged Middle.

    The two doctors note that no matter how the story spins from the denizens of the anti-fat camp, one piece of their advice remains staunchly constant: "You should sharply limit your intake of saturated fats." But will saturated fats really increase your risk of heart disease and raise your cholesterol? In a word, no. In fact, humans need them, and here are just a few reasons why:

    1) Improved cardiovascular risk factors

    Saturated fat plays a key role in cardiovascular health. The addition of saturated fat to the diet reduces the levels of a substance called lipoprotein(a) that correlates strongly with risk for heart disease. Research has shown that when women diet, those eating the greatest percentage of the total fat in their diets as saturated fat, lose the most weight.

    2) Stronger bones

    Saturated fat is required for calcium to be effectively incorporated into bone. According to one of the foremost research experts in dietary fats and human health, Dr. Mary Enig, Ph.D., there's a case to be made for having as much as 50 percent of the fats in your diet as saturated fats for this reason.

    3) Improved liver health

    Saturated fat has been shown to protect the liver from alcohol and medications, including acetaminophen and other drugs commonly used for pain and arthritis.

    4) Healthy lungs

    For proper function, the airspaces of the lungs have to be coated with a thin layer of lung surfactant. The fat content of lung surfactant is 100 percent saturated fatty acids. Replacement of these critical fats by other types of fat makes faulty surfactant and potentially causes breathing difficulties.

    5) Healthy brain

    Your brain is mainly made of fat and cholesterol. The lion's share of the fatty acids in the brain are actually saturated. A diet that skimps on healthy saturated fats robs your brain of the raw materials it needs to function optimally.

    6) Proper nerve signaling

    Certain saturated fats, particularly those found in butter, lard, coconut oil, and palm oil, function directly as signaling messengers that influence metabolism, including such critical jobs as the appropriate release of insulin.7) Strong immune system

    Saturated fats found in butter and coconut oil (myristic acid and lauric acid) play key roles in immune health. Loss of sufficient saturated fatty acids in white blood cells hampers their ability to recognize and destroy foreign invaders, such as viruses, bacteria, and fungi.

    Source: Four Hour Work Week September 6, 2009

    Dr. Mercola's Comments:

    A misguided fallacy that persists to this day is the belief that saturated fat will increase your risk of heart disease and heart attacks. This is simply another myth that has been harming your health for the last 30 or 40 years.

    The truth is, saturated fats from animal and vegetable sources provide a concentrated source of energy in your diet, and they provide the building blocks for cell membranes and a variety of hormones and hormone-like substances.

    When you eat saturated fats as part of your meal, they slow down absorption so that you can go longer without feeling hungry. In addition, they act as carriers for the important fat-soluble vitamins A, D, E and K. Dietary fats are also needed for the conversion of carotene to vitamin A, for mineral absorption, and for a host of other biological processes.

    Saturated fats are also:

    The preferred fuel for your heart, and also used as a source of fuel during energy expenditure Useful antiviral agents (caprylic acid) Effective as an anticaries, antiplaque and anti-fungal agent (lauric acid) Useful to actually lower cholesterol levels (palmitic and stearic acids) Modulators of genetic regulation and prevent cancer (butyric acid) If the fact that saturated fats are actually good for you sounds conflicting, at least in terms of what is repeated by public health agencies, I urge you to read Mary Enig and Sally Fallon's classic article The Truth About Saturated Fats. It is one of the best and most thorough introductions to this topic, and you can read through it in just a few minutes.

    Have You Heard of the Lipid Hypothesis?

    If not by name, you've certainly heard of the concept behind the "lipid hypothesis," and that is that dietary fat causes heart disease.

    This flawed theory was largely spread by Ancel Keys, a diet researcher for whom military K-rations are named, and it was because of the lipid hypothesis that Americans were soon encouraged to substitute vegetable-based fats for animal fats, and to avoid red meat completely.

    However, when Keys published his analysis that claimed to prove the link between dietary fats and coronary heart disease, he selectively analyzed information from only six countries to prove his correlation, rather than comparing all the data available at the time - from 22 countries.

    As a result of this "cherry-picked" data, government health organizations began bombarding the public with advice that has contributed to the diabetes and obesity epidemics going on today: eat a low-fat diet.

    Of course, as Americans cut out nutritious animal fats from their diets, they were left hungry. So they began eating more processed grains, more vegetable oils, and more high-fructose corn syrup, all of which are nutritional disasters.

    What About the Studies That DO Show a Link Between Fat and Heart Disease?

    Keys believed that dietary fat was causing heart disease in Americans back in the 1950s, and he soon got others to jump on the bandwagon.

    Even the American Heart Association, which concluded in 1957 that "the evidence that dietary fat correlates with heart disease does not stand up to critical examination," changed its position in 1960. Why? Because Keys was on the committee issuing a new report that a low-fat diet was advised for people at risk of heart disease. Sadly, the theory continued to be accepted as nutritional wisdom, even though clinical trials found no connection.

    There are, however, some studies that have found a link between fat and heart disease, and they are often used by saturated fat opponents to "prove" their case.

    The problem lies in the fact that most of these studies make no effort to differentiate between saturated fat and trans fat. I believe this is the missing link.

    If researchers were to more carefully evaluate the risks of heart disease by measuring the levels of trans and saturated fat, I believe they would find a completely different story.

    Trans fat is known to increase your LDL levels, or "bad" cholesterol, while lowering your levels of HDL, known as "good" cholesterol, which is the complete opposite of what you need in order to maintain good heart health. It can also cause major clogging of arteries, type-2 diabetes and other serious health problems.

    On the other hand, your body needs some amount of saturated fat to stay healthy. It is virtually impossible to achieve a nutritionally adequate diet that has no saturated fat. What you don't need, however, are trans fats.

    Further, there are some people who do well with a low-saturated-fat diet - the one-third who are carb nutritional types. Even then, however, some animal fats are necessary and healthy, and two-thirds of people actually require moderate- to high-saturated-fat diets to thrive.

    Healthy Sources of Saturated Fats to Add to Your Diet

    Saturated fat is not the root of all evil - and it is NOT to blame for the modern disease epidemics facing Americans. Saturated fat is actually an incredibly healthy, nourishing and all natural fat that humans have been thriving on for generations. Again, as Fallon and Enig point out:

  • Saturated fatty acids constitute at least 50 percent of your cell membranes. They are what gives your cells necessary stiffness and integrity.

  • They play a vital role in the health of your bones. For calcium to be effectively incorporated into your skeletal structure, at least 50 percent of your dietary fats should be saturated.

  • They lower Lp(a), a substance in your blood that indicates proneness to heart disease.

  • They protect your liver from alcohol and other toxins, such as Tylenol and other drugs.

  • They enhance your immune system.

  • They are needed for the proper utilization of essential fatty acids. Elongated omega-3 fats are better retained in your tissues when your diet is rich in saturated fats.

  • Saturated 18-carbon stearic acid and 16-carbon palmitic acid are the preferred foods for your heart, which is why the fat around your heart muscle is highly saturated. Your heart draws on this reserve of fat in times of stress. Short- and medium-chain saturated fatty acids have important antimicrobial properties.

  • They protect you against harmful microorganisms in your digestive tract.

    So please do not shun saturated fats from your diet. If you'd like to get the most tailored information about which fats, and how much of them, to include in your optimal diet, first find out your nutritional type. Then, make sure your meals include some of these delicious and healthy sources of saturated fat:

  • Grass-fed organic beef and beef fat
  • Naturally raised lamb
  • Organic raw dairy products (butter, cheese, milk, cream)
  • Coconut oil




    4 Reasons Love Coconut Oil(Natural News)



    (NaturalNews) Few foods, with the possible exception of eggs, have had their reputations so completely demolished in the 20th century as coconut oil. Even as late as the 1990s, this edible oil, which is extracted from the kernels or flesh of matured coconuts, continued to be demonized in the media as a great contributor to heart disease due to its significant saturated fat content.

    Fortunately, modern society is beginning to understand that the saturated fat present in coconut oil is, contrary to popular belief, actually highly beneficial. This understanding was, in part, due to a growing body of evidence suggesting that populations who consumed large quantities of coconut oil, such as the Tokelauan and Kitavan people of the South Pacific, were among the healthiest people on Earth. This evidence prompted a growing number of scientists to investigate the benefits of coconut oil.

    Coconut oil is an unbeatable source of saturated fat

    According to Self's "NutritionData," one tablespoon of coconut oil contains 14 grams of total fat, of which 12 grams are saturated. Whereas the saturated fat found in most other foods, such as meat and cheese, is mostly comprised of long-chain triglycerides (LCTs), the saturated fat found in coconut oil is mostly comprised of medium-chain triglycerides (MCTs). Unlike LCTs, which need to be broken down in the intestines before our bodies can use them as fuel, MCTs are metabolized extremely quickly and rarely stored in the body as fat cells. These MCTs are the source of all of the benefits listed below.

    Coconut oil can reduce abdominal obesity

    Due to its concentrations of MCTs, long-term consumption of coconut oil has actually been linked to weight loss, not weight gain. A Brazilian study published in Lipids in 2009, found that women who consumed 30 milliliters of coconut oil daily for a 12 week period experienced a reduction in BMI and waist circumference. A group of women who consumed equal amounts of soybean oil, which contains LCTs, during the same period did not experience the same benefits.

    Coconut oil kills bacteria, viruses and fungi

    Almost 50% of the MCTs found in coconut oil is lauric acid, a 12-carbon saturated fatty acid that our bodies convert into monolaurin. Monolaurin is one of the natural world's greatest antivirals, antibacterials and antifungals. In fact, Dr. Joseph Mercola claimed that monolaurin can destroy lipid-coated viruses, such as measles, herpes, influenza, most pathogenic bacteria and even HIV. These claims are now being studied by science. One study published in the Journal of Medicinal Food in 2007, found that coconut oil is extremely effective at killing Candida albicans, a common yeast infection in humans. Another study published in the Journal of Bacteriology in 2000 discovered that coconut oil can help kill Staphylococcus aureus, which is a common cause of skin conditions and respiratory diseases.

    Coconut oil can maintain mental health

    It is a well-known fact that inadequate amounts of our brain's main fuel supply, glucose, is the leading cause of cognitive disorders, such as Alzheimer's disease and dementia. According to researcher Dr. Mary Newport, coconut oil can help prevent these diseases due to the high concentrations of ketone bodies in its MCTs, which function as an alternative fuel source. "Humans do not normally have ketone bodies circulating and available to the brain unless they have been starving for a couple of days or longer, or are consuming a ketogenic (very low carbohydrate) diet, such as Atkins," says Newport. "In Alzheimer's disease, the neurons in certain areas of the brain are unable to take in glucose due to insulin resistance and slowly die off... If these cells had access to ketone bodies, they could potentially stay alive and continue to function."




    Gout isn't always easy to prove: Study finds CT scans help catch cases traditional test misses (MNT)



    Gout is on the rise among U.S. men and women, and this piercingly painful and most common form of inflammatory arthritis is turning out to be more complicated than had been thought. The standard way to check for gout is by drawing fluid or tissue from an affected joint and looking for uric acid crystals, a test known as a needle aspirate. That usually works, but not always: In a new Mayo Clinic study, X-rays known as dual-energy CT scans found gout in one-third of patients whose aspirates tested negative for the disease. The CT scans allowed rheumatologists to diagnose gout and treat those patients with the proper medication.

    The results are published in the Annals of the Rheumatic Diseases, the European League Against Rheumatism journal.

    The study tested the usefulness of CT scans in finding uric acid crystals around joints across a spectrum of gout. The researchers found CT scans worked particularly well in detecting gout in patients who had experienced several gout-like flares but whose previous needle aspirates came back negative. After CT scans found what appeared to be uric acid crystals, ultrasound-guided aspirates were taken in those areas and tested for urate crystals.

    "These were in part patients that had been falsely diagnosed with diseases like rheumatoid arthritis or labeled with a different type of inflammatory arthritis, resulting in a completely different and often not effective treatment approach," says first author Tim Bongartz, M.D., a Mayo Clinic rheumatologist. "And there were patients who remained undiagnosed for several years with, for example, chronic elbow symptoms or Achilles tendon systems, where the CT scan then helped us to pick up uric acid deposits."

    The study isn't meant to suggest that CT scans should be the first test used to look for gout, Dr. Bongartz says. Needle aspirates work well in most cases, and the research showed CT scans weren't as effective a diagnostic tool among patients having their first gout flare-up, he says. In some of those acute gout cases, needle aspirates found uric acid crystals, but CT scans didn't.

    Gout is often thought of as a man's disease and associated with sudden sharp, burning pain in the big toe. It's true that until middle age, more men than women get gout, but after menopause, women catch up in the statistics. And gout can hit more than the big toe: Other joints including parts of the feet, ankles, knees, fingers, wrists and elbows can be affected.

    "The first flare of gout most commonly occurs in the big toe, but gout can affect pretty much every joint in the body, and the more gout flares you have the more likelihood that other joint areas will be affected," Dr. Bongartz says.

    Five percent of adult African-Americans and 4 percent of whites in the U.S. have gout. The nation's obesity epidemic is thought to be a factor behind the increase in gout cases.

    An accurate and early gout diagnosis is crucial because gout patients are treated with different medication than people with other forms of inflammatory arthritis, and proper medication and dietary changes can help prevent further gout attacks and the spread of the disease to other joints.

    "What we are learning from the dual-energy CT scans has really changed our perception of where gout can occur and how it can manifest," Dr. Bongartz says. "The ability to visualize those deposits clearly broadens our perspective on gout." [back to the top]




    An Upside to Gout: 

    It May Offer 
  • Alzheimer's Protection 
  • (By Nicholas Bakalar
  •  nytimes blog)
  • Gout, a form of arthritis, is 
  • extremely painful and 
  • associated with an increased 
  • risk for cardiovascular 
  • problems. But there is a bright 
  • side: It may be linked to a 
  •  reduced risk for Alzheimer's disease.

  • Researchers compared 59,204 
  • British men and women with 
  • gout to 238,805 without the 
  • ailment, with an average age 
  • of 65. Patients were matched 
  • for sex, B.M.I., smoking, 
  • alcohol consumption and 
  • other characteristics. The 
  • study, in The Annals of the 
  • Rheumatic Diseases, followed 
  • the patients for five years.

    They found 309 cases of 
  • Alzheimer's among those with 
  • gout and 1,942 among those 
  • without. Those with gout, 
  • whether they were being 
  • treated for the condition or not, 
  • had a 24 percent lower risk of 
  • Alzheimer's disease.

    The reason for the connection is 
  • unclear. But gout is caused by 
  • excessive levels of uric acid in 
  • the blood, and previous studies 
  • have suggested that uric acid 
  • protects against oxidative 
  • stress. This may play a role in 
  • limiting neuron degeneration.

    "This is a dilemma, because 
  • uric acid is thought to be bad, 
  • associated with heart disease 
  • and stroke," said the senior 
  • author, Dr. Hyon K. Choi, a 
  • professor of medicine at 
  • Harvard. "This is the first 
  • piece of data suggesting that 
  • uric acid isn't all bad. Maybe 
  • there is some benefit. It has 
  • to be confirmed in 
  • randomized trials, but that's 
  • the interesting twist in this 
  • story."


  • 1 comment:

    1. Thanks for sharing such beautiful information with us. I hope you will share some more information about gout flare pain.Please keep sharing.
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