Final Warning 3

 Current  Covid-19  vaccine  technologies 

• All  of them  are  targeted  at inducing   specific Abs to S-protein  (S1-  RBD),  so none of  them prevents  viral  replication if Abs  are too  low in  concentration  or  affinity  

 • They cannot  control replication of more infectious  CoV  variants  and  may even drive  immune escape  (e.g.,  when  fully  vaccinated  subjects  are  exposed to  viral  variants) 

• Are they  safe?   

-  yes,  at the level  of  the  individual   -  absolutely not,  for  human  populations  exposed to Covid-19  pandemic 

• Are they  efficacious for  protecting  against disease?   

-  yes,  at the level  of  the  individual -  absolutely  not, for  human  populations  exposed to Covid-19  pandemic Abs:  Antibodies -   

Univac    -  Strictly  Confidential  –  June  2016  - -  3  

- Author:  Dr.  G.  Vanden  Bossche;  NONCONFIDENTIAL;  DO COPY;  DO DISTRIBUTE