Thursday, April 22, 2021

Recent advances in curing asthma

 1992 Reviews in Medicine 

Recent advances in asthma 

By Peter J. Barnes and Tak H. Lee

 Department of Thoracic Medicine , National Heart and Lung Institute, Dovehouse Street,  SW36LY and Department of Allergy and Allied Repiratory Disorders, United Medical and Dental School, Guy's Hospital, London, SE], UK

Introduction

There  recently been important advances in our undersanding of asthma mechanisms and treatment. 

Water Cures Asthma

Here you will learn something I discovered as a child, that sea salt and water cures asthma.


Please NOTE: While medical health sites say steer clear of websites that claims a cure for asthma saying they do not exist, consider this. We are not selling anything. We are applying the most fundamental principles of health optimization, the very ones used in the hospital, the saline IV, only the oral version of it. This is something you can try for yourself, see if it works and decide for yourself. We are not recommending discontinuing your medications. We always recommend you follow your doctors directions. Until clinical trials are completed, this is an option, especially if you should ever be an emergency such as not having your inhalers or asthma medications.

Dr. B says that asthma is a sign and symptom of chronic unintentional fluid and electrolyte imbalance.

You will not find this on the top of the list of asthma causes. You will find, if you try it, that it works. I know because of learning this first hand as a child before the book, Your Bodies Many Cries for Water was even a theory Dr. B was considering. It ended my asthma as a child, this I have no doubt.


In later life, a new challenge faced me. It took years to find that I was experiencing an often misdiagnosed asthma, called cough variant asthma.

Cough Variant Asthma vs Chronic Bronchitis, the Differences.


Asthma Signs and Symptoms


Asthma Attack Home Remedy


Natural Cures For Asthma


Natural Remedies for Asthma


Asthma Natural Treatment


Alternative Medicine for Asthma


Asthma Remedy


Cause of Asthma


Asthma Cured with Sea Salt and Water

I unknowingly treated and cured my asthma as a child. It was thought that I grew out of the asthma. This was before we knew the effects of chronic smoke exposure. This is before we knew what COPD was. This is before the many modern treatments for asthma that exist today.

The treatment I discovered as a child was simply a combination of becoming a salt-a-holic and drinking alkaline water. What we know now is that the combination of salt and water help improve asthma symptoms. Asthma is the result of inflammation. Adding alkaline water, causing the body to become more alkaline, can help reduce inflammation.


We will review the asthma signs, symptoms, natural treatments and remedies. Water cures is an amazingly simple solution to asthma. Although there is little science, there are a number of doctors who are using this with their patients. They use it because it works.


Join us on a journey of the mind to learn how many have ended their affliction with asthma simply using sea salt and water. The information here is free. We are not selling this wisdom. It is yours free to use.


Good health to you and yours.


Dog Asthma: Water Cures Can Help

Dog Asthma Treatment

Dog Asthma Symptoms

Water Cures Asthma in Dogs

Natural Cures For Asthma

How Salt and Water Cures Asthma

In time we will be adding more information on each of the following topics. If you want something sooner, please post a comment below. The topics getting the most response will be answered first.

More Causes of Asthma

We will be adding more information on how water and sea salt cures asthma. Please come back and learn more about water cures.

More Respiratory System.

How Water Cures Asthma The Water Cure

Asthma is now recognized as a disease of the airways which  involves a special type inflammation, characterized by the presence of activated mastcells, eosinophils and T-lymphocytes. There has been a growing recognition that chronic rather than acute inflammatory events are more relevant to understanding the underlying mechanisms in asthma and the role of cytokines, as mediators of chronic inflammation, has been an area of very rapid development. At the same time the approach to asthma treatment has changed, with a much greater emphasis on the earlier and more widespread use of inhaled anti-inflammatory drugs, and  inhaled steroids. There has also been an increased understanding of the mechanisms of action of existing anti-asthma therapies, but at the same time questions have been raised about the safety of some treatments. This has prompted the search for novel anti-asthma therapies, based on our current understanding of pathophysiological mechanisms. The literature on asthma is vast and we do not intend to provide an exhaustive or comprehensive review, but have concentrated on some areas where there have been advances in knowledge which have clinical and therapeutic relevance. 

Epidemiology

Asthma is one of the commonest diseases in industrialized countries and has a large economic impact in terms of health and loss of time from work. The total costs for asthma in the USA were recently estimated as $6.2billion (1992 figure), representing 1%  of all US healthcare costs. There have recently been several studies which indicate that the prevalence of asthma has increased over the last few years. A study in Finnish army conscripts has revealed a marked in the number of recruits with a diagnosis of asthma. In the UK there is evidence for  trends. Admission of children to hospital with asthma attacks has more than doubled over the last 10 years in the UK.  The reasons for this increase in morbidity are uncertain, since it is difficult to identify a single factor in the environment which has changed over the same time frame. There has been concern about air pollution, but little direct evidence to link specific changes in air quality to worsening of asthma. It  is likely that an interaction between different air pollutants is important. A recent study investigated whether a common air pollutant, ozone, had any influence on allergen challenge in a group of mild asthmatic patients. A concentration of ozone as low as 0.12 parts per million, which itself had no effect on airway function let to an increase in both the early and late response to inhaled allergen. Nitrogen dioxide(NO2) is a pollutant which is particularly associated with car exhaust fumes but there are few studies which have examined its airway effects or whether it interacts with other air pollutants or with allergen. 

Allergen exposure is probably the most important factor in determining asthma severity. Exposure to allergen in early life is an important risk factor  in the subsequent development of asthma. There is a striking association between the dust levels of Der pl (the major allergen of house dust mite) at the time of birth and the prevalence of asthma at 11 years of age, although current levels of exposure have been a confounding factor in this study. Increased allergen exposure has been implicated in the increase in asthma and the 'tight' houses, with poor ventilation and central heating increasingly found in temperate climates, may increase the house dust mite population and the concentration of indoor pollutants such as cigarette smoke.

Another possible factor

contributing to the increased

morbidity

and even mortality of

asthma may be the use

of anti-asthma medication,

and in particular the

excessive use of inhaled

beta (β)-agonists.

The pathology of the

asthmatic airway mucosa

Early studies in patients

dying from status

asthmaticus revealed

marked inflammation

of the bronchial tree.

Recent evidence using

fibre optic bronchoscopy

and biopsy has confirmed

that similar changes are

also present in asthmatic

patients during life. There

is extensive damage of

the epithelium; the

numbers of epithelial cells

recovered by bronchoalveolar lavage correlate

with the extent of air ways

hyperresponsiveness.

Recentmorphological studies

using transmission

electron microscopy and

the use of monoclonal

antibodies to differentiate

collagen subtypes, have

shown that bronchial

epithelial basement

membrane is of normal

thickness in asthma.

However, there is a

dense deposition of

collagen fibres in the

a

lavage
correlate
with
the
extent
of
airways
hyperresponsiveness.'°
Recent
morphological
studies
using
transmission
electron
microscopy
and
the
use
of
monoclonal
antibodies
to
differentiate
collagen
subtypes,
have
shown
that
bronchial
epithelial
basement
memb-
rane
is
of
normal
thickness
in
asthma.'1
However,
there
is
a
dense
deposition
of
collagen
fibres
in
the
subepithelial
region.
This
consists
predominantly
of
collagen
types
3
and
5,
together
with
fibronectin
but
not
laminin.
The
cellular
source
of
the
subepithelial
collagen
may
be
the
myofibroblast."
Mast
cells
Mast
cells
in
the
asthmatic
airway
mucosa

.This consists

predominantly of

collagen types 3 and 5,

together with fibronectin

but not laminin. The

cellular source of the sub

epithelial collagen may be

the myofibroblast."

Mastcells

Mastcells in the asthmatic

airway mucosa

are degranulated.

Considerable interest has

centred upon the recent

observation that rodent

mastcells synthesize a

wide range of cytokines

upon IgE- mediated

activation. There is, as

yet, limited data on the

generation of cytokines

for human mastcells.

Steffen et al. reported

the presence of tumour

necrosis factor alpha (TNFx)

in mastcells/basophils

derived from the culture

of human bone marrow.

Preliminary data suggest

that purified human

pulmonary mastcells

contain TNF a bio-activity.



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smoke

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