Your Pancreas Has a Clock

 Your Pancreas Has a Clock - And It Shuts Down Before Dinner

... your entire life, binding to receptors on the beta cells that no dietary intervention can override. Your glut transporters retract from the muscle cell surface as the day progresses. The glucose that arrived at noon met transporters ready to receive it. The glucose that arrives at 9 meets a reduced compliment. Your gut bacteria chain shifts. The day time community that ferments and processes efficiently yields to an evening community that extracts more calories from less food. 

 Your liver clocks out. The enzyme activity that process fructose and lipids of peak efficiency 12 hours ago has declined to its circadian minimum. 

 Your sympathetic nervous system has shifted to parasympathetic dominance. 

 The thermogenic cost of digesting the meal has dropped to a fraction of its morning value. The meal you eat at 8 PM, in the evening is not the meal you think you are eating. 

It is the same food meeting, a different body, a body that has already begun shutting down every system required to process it. 

The clock is not optional. A clock is not negotiable. The clock is the metabolism.

THE CLOCK IS THE METABOLISM