Showing posts with label stem. Show all posts
Showing posts with label stem. Show all posts

Tuesday, February 28, 2017

Where Are Stem Cells Found In The Body?

Question:

Where are stem cells found in the body?

Answer:

Stem cells come from different places, depending on the type of stem cell you are talking about.

In leukemia and lymphoma, stem cells may be transplanted into the person with cancer to help replenish the bone marrow for production of new blood cells. In these cases, the stem cells come from the bone marrow or bloodstream of a living donor. Stem cells of this type are also known as adult stem cells and, more specifically, hematopoietic stem cells, since they give rise to blood cells.

 

The stem cell transplants performed in people with cancer do not use any embryonic cells.When it comes to stem cell research, however, stem cells might come from any number of different sources, including from specialized tissues of living human donors or sacrificed human embryos.

Stem Cells for Transplants (HSCT) in Cancer
The bone marrow makes all of your blood cells: red cells, white cells, and other cells called megakaryocytes that make platelets to help with clotting. Hematopoietic stem cells within the bone marrow are the “parents” or progenitors of all of these different cell types that form the blood.

These hematopoietic stem cells are transplanted into a person with cancer to help replenish healthy bone marrow and blood cells; high doses of chemotherapy kill cancer cells effectively, but also kill stem cells in the bone marrow. So, shortly after chemotherapy, stem cells are given into a vein, much like a blood transfusion.
The cells take some time to settle into the bone marrow and begin to grow and make new healthy blood cells.
 
Bone Marrow vs. Peripheral Blood

Years ago, the only source for stem cells used in transplants was bone marrow. Then a small number of blood-forming stem cells was discovered circulating out in the peripheral bloodstream.

Doctors learned to collect these stem cells from the circulating blood -- and to use them for transplants. This type of transplant, known as a peripheral blood stem cell transplant, or PBSCT, has become more common than transplants from bone marrow, however, both methods are in use today.

Other Stem Cells

In other cases, and in the absence of additional information, the term "stem cell" is ambiguous as to the source of the cells. Additional descriptors are needed to tell you what type of stem cell it is and where it comes from. There are currently three main categories of stem cells; each one has a different source:
Embryonic stem cells are the most controversial stem cells since they come from human embryos that have been destroyed, or harvested for science.

According to the National Institutes of Health (NIH) stem cells from sacrificed human embryos were first grown in a laboratory in 1998; they were originally “created for reproductive purposes,” but when they were no longer needed, they were donated with informed consent of "the donor" -- presumably the egg donor, but possibly the sperm donor -- or perhaps both -- in any case, consent obviously does not refer to the developing human embryo.

Children are usually deemed unable to provide consent for medical procedures prior to the age 16 years; sometimes 18 years of age is used as the threshold age for consent.

Adult stem cells are also called somatic stem cells. These stem cells are obtained without the destruction of a human embryo. Hematopoietic or blood-forming stem cells are an example of this kind of stem cell, and they have been used for generations. The term “somatic” means “body” and underscores that these cells come from a living body and not from a sacrificed embryo. Scientists have found adult stem cells in many more tissues than once thought possible. According to the NIH, adult stem cells have been found in many organs and tissues, including brain, bone marrow, peripheral blood, blood vessels, skeletal muscle, skin, teeth, heart, gut, liver, ovarian cells, and testis.

Induced pluripotent stem cells, or iPSCs, are adult cells that have been genetically reprogrammed to be more like embryonic stem cells. The source is adult or somatic cells and not embryonic cells, but these are adult cells that have undergone genetic engineering.

According to UCLA's Center for Regenerative Medicine and Stem Cell Research, iPSCs usually start out as skin cells or blood cells, which then undergo genetic programming. It is currently possible to produce almost any desired cell type from any patient's cells. Laboratory research has shown promising results using these cells to correct a number of genetic disorders of the blood, nervous system and muscles.
Updated February 2016, TI.

Sources:
National Institutes of Health. Stem Cell Information. Stem Cell Basics
Simara P, Motl JA, Kaufman DS. Pluripotent Stem Cells and Gene Therapy. Transl Res. 2013;161(4):284-292.
Al-Shamekh S, Goldberg J. Retinal Repair with Induced Pluripotent Stem Cells. Transl Res. 2014;163(4):377-386.
Finkbeiner SR, Spence JR. A Gutsy Task: Generating Intestinal Tissue from Human Pluripotent Stem Cells. Digestive Diseases and Sciences. 2013;58(5):1176-1184.
Priori SG, Napolitano C, Di Pasquale E, Condorelli G. Induced pluripotent stem cell–derived cardiomyocytes in studies of inherited arrhythmias. J Clin Invest. 2013;123(1):84-91.
UCLA. Induced Pluripotent Stem Cells (iPS)

 

Stem Cell Year-in-Review 2016

Stem Cell Year-in-Review 2016
If we picked one word to define the past year in the stem cell field, it would have to be ‘therapy.’

While many important developments impacted the field, two that garnered significant public, political and scientific attention in 2016 were the proliferation of clinics using unproven stem cell “therapies,” and the steps forward in therapeutic modification of human oocytes (unfertilized eggs) through a process called mitochondrial replacement therapy (MRT).

Within the stem cell field, unproven stem cell therapies, or “treatments” that lack rigorous scientific proof of their safety and effectiveness, have been a growing concern. Clinics often offer these types of treatments directly to consumers, marketing them online or in recruiting seminars, often at substantial cost. The treatments typically use autologous stem cells (those obtained from one’s body) to treat everything from bad knees to incurable disease such as ALS or Parkinson’s. In some countries, this phenomenon traditionally has been called stem cell tourism because it involved travel to another country with less stringent regulations to obtain treatment. Two publications1,2 in 2016 debunked that concept, showing these clinics are found throughout the world. The U.S. alone has an estimated 570 clinics. That puts the U.S. among the countries with the highest number of such clinics, along with India, Mexico, China, Australia, United Kingdom, Thailand, Malaysia and Germany.

Like many countries, the U.S. struggles to regulate unproven stem cell therapies. In 2016, the Food and Drug Administration (FDA), the branch of government charged with regulating cellular therapies, took action to address these issues, proposing revised guidelines that could change how stem cells, especially autologous stem cells, are regulated. The ISSCR was among the organizations and individual scientists that supported the need for careful oversight and regulation of the therapeutic application of stem cells. The FDA has yet to issue a final ruling, but a Perspective article written by three FDA executives published in the New England Journal of Medicine may provide insight into their thinking.

Another big story in 2016 was the first reported use of MRT in humans. This relatively new technology has shown to be effective in animal models for intercepting mitochondrial disease before it’s passed from mother to child. The approach works by replacing the mother’s mutant mitochondria responsible for disease with healthy mitochondria from a donor. The chimeric oocytes (that contain the mother’s nuclear DNA and the donor’s mitochondria) then undergo fertilization through standard IVF methods.

A U.S. fertility specialist reported the birth of a baby boy from a mother who was a carrier for mitochondrial disease that lead to the death of her previously-born children. The MRT procedure is not approved in the U.S., so doctors performed it in Mexico, which led to many concerns within and outside the scientific community. Among them, how do regulatory agencies and the scientific community deal with procedures approved in some countries but not others? Whether and how should we advance human health using technology that alters a natural state? How far should science be applied in influencing health-related outcomes?

This concern was also brought to the forefront of the scientific and public consciousness when a report by Chinese scientists described the use of CRISPR-Cas to modify a gene in human embryos making them resistant to HIV infection [to learn more about CRISPR-Cas, read our previous blog].  Although the embryos were not viable and not intended for clinical use, this proof-of-principle research raised ethical concerns and emphasized the need to continue to have discussions on the scientific and social impact of this technology and its use in countries around the world.

While 2016 saw many articles on unproven stem cell therapies, and the controversial use of MRT, there were many positive stories about potential stem cell-derived therapies that are successfully moving into the clinic for testing. Interventions for macular degeneration, stoke, cancers, and sickle cell disease, among others, are in approved clinical trials in California (U.S.), London, Japan, and elsewhere. These trials, unlike the unproven therapies, have been approved by the appropriate regulatory agencies and will be rigorously tested so that the risks and benefits are more fully understood before (hopefully) being made available to patients. We look forward to continued advances in 2017 that support the rigorous, ethical standards set forth in the 2016 Guidelines for Stem Cell Research and Clinical Translation, and help address issues of human health around the world.


Second Chinese team reports gene editing in human embryos

Study used CRISPR technology to introduce HIV-resistance mutation into embryos.

 
Early-stage human embryos have been edited by scientists.
Researchers in China have reported editing the genes of human embryos to try to make them resistant to HIV infection. Their paper1 — which used CRISPR-editing tools in non-viable embryos that were destroyed after three days — is only the second published claim of gene editing in human embryos.
In April 2015, a different China-based team announced that they had modified a gene linked to a blood disease in human embryos (which were also not viable, and so could not have resulted in a live birth)2. That report — a world first — fuelled global deliberations over the ethics of modifying embryos and human reproductive cells, and led to calls for a moratorium on even such proof-of-principle research.
At the time, rumours swirled that other teams had conducted similar experiments. Sources in China told Nature’s news team that a handful of papers had been submitted for publication. The latest paper, which appeared in the Journal of Assisted Reproduction and Genetics on 6 April, might be one of these. Nature’s news team has asked the paper’s corresponding author, stem-cell scientist Yong Fan, for comment, but had not heard from him by the time of this report.

HIV resistance

In the paper, Fan, who works at Guangzhou Medical University in China, and his team say that they collected a total of 213 fertilized human eggs between April and September 2014. The fertilized eggs, donated by 87 patients, were unsuitable for implantation as part of in vitro fertility therapy, because they contained an extra set of chromosomes.
Fan’s team used CRISPR–Cas9 genome editing to introduce into some of the embryos a mutation that cripples an immune-cell gene called CCR5. Some humans naturally carry this mutation (known as CCR5Δ32) and they are resistant to HIV, because the mutation alters the CCR5 protein in a way that prevents the virus from entering the T cells it tries to infect.
Genetic analysis showed that 4 of 26 human embryos targeted were successfully modified. But not all the embryos’ chromosomes harboured the CCR5Δ32 mutation — some contained unmodified CCR5, whereas others had acquired different mutations.
George Daley, a stem-cell biologist at Children’s Hospital Boston in Massachusetts, says that the paper’s main advance is the use of CRISPR to introduce a precise genetic modification successfully. “This paper doesn’t look like it offers much more than anecdotal evidence that it works in human embryos, which we already knew,” he says. “It’s certainly a long way from realizing the intended potential” — a human embryo with all its copies of CCR5 inactivated.
“It just emphasizes that there are still a lot of technical difficulties to doing precision editing in human embryo cells,” says Xiao-Jiang Li, a neuroscientist at Emory University in Atlanta, Georgia. He thinks that researchers should work out these kinks in non-human primates, for example, before continuing to modify the genomes of human embryos using techniques such as CRISPR.

Ethics of experiments

Tetsuya Ishii, a bioethicist at Hokkaido University in Sapporo, Japan, sees no problem with how the experiments were conducted — a local ethics committee approved them, and the egg donors gave their informed consent — but he questions their necessity. “Introducing CCR5Δ32 and trying repair, even in non-viable embryos, is just playing with human embryos,” Ishii says.
Fan's team writes in the paper that proof-of-principle experiments for human-embryo editing such as theirs are important to conduct while the ethical and legal issues of germline modification are being hashed out. “We believe that any attempt to generate genetically modified humans through the modification of early embryos needs to be strictly prohibited until we can resolve both ethical and scientific issues,” they write.
Daley sees a stark contrast between Fan’s work and research approved in February by UK fertility regulators that will allow CRISPR genome editing of human embryos. Those experiments, led by developmental biologist Kathy Niakan at the Francis Crick Institute in London, will inactivate genes involved in very early embryo development, in hopes of understanding why some pregnancies terminate. (The work will be done in viable embryos, but the researchers' licence requires that experiments be stopped within 14 days.)
Earlier this year, developmental biologist Robin Lovell-Badge, also at the Francis Crick Institute, told Nature that he thought that the carefully considered UK approval might embolden other researchers who are interested in pursuing embryo-editing research. “If they've been doing it in China, we may see several manuscripts begin to appear,” he said.
Whereas Niakan's work is answering questions intrinsic to embryology, Fan's work is establishing proof of principle for what would need to be done to generate an individual with resistance to HIV, Daley adds. “That means the science is going forward before there’s been the general consensus after deliberation that such an approach is medically warranted," he says.
 

Tuesday, February 14, 2017

Infuse your Tissues with Stem Cell Nutrition and Feel Your Best Every Day!

Product Fact Sheet

Infuse your Tissues with Stem Cell Nutrition and Feel Your Best Every Day!
A multi-faceted dietary supplement that does what other supplements cannot.

ST-5™ with MigraStem™ quickly and conveniently 
provides the daily balanced nutrition you need to 
maximize the use of your body’s own stem cells and 
create a “feel good” sense of vitality and stamina. 
This advanced nutritional multi-supplement 
addresses health at the cellular level— feeding your 
cells what it needs so your body can function at its 
best.

ST-5 with MigraStem contains 5 specialized blends 
including the exclusive MigraStem. Loaded with 
15 grams of plant-based protein, 9 grams of fiber, 
ST-5 with MigraStem also provides 20 vitamins 
and minerals, antioxidants, prebiotics, exotic 
superfoods and digestive enzymes— all in one 
scoop. A delicious nutrient boost to your favorite 
healthy beverage, ST-5 with MigraStem provides 
everything your body needs to thrive.
MigraStem Power.

ST-5 with MigraStem is the only nutritional 
supplement available that contains the 
patent-pending MigraStem blend. MigraStem 
is a powerful, proprietary blend of natural 
ingredients that has been documented to assist 
the body’s natural renewal process by 
encouraging your body’s own stem cells to 
migrate — following the release and 
circulation of them — into tissue.†

Once in the tissue, your stem cells reproduce and 
become new healthy cells of that tissue. Working 
in-tandem with Stemtech’s SE3™and StemFlo®, 
ST-5 with MigraStem further supports the 
migration of your body’s own stem cells into 
tissues and organs in need. This trio of products 
orchestrates a greater level of stem cell nutrition 
by supporting your daily renewal process.

Key Benefits
 Optimizes the Migration of your body’s own stem 
cells†
 Supports weight management†
 High in dietary fiber - 10g
 Supports healthy digestion with prebiotics and 
digestive enzymes†
 Supports sustained energy†
 Excellent source of protein - 15g

 Rich source of your daily vitamins and minerals
Less Than 1 Gram of Sugar
Unique Protein Blend
67% More Fiber
33% More Digestive Enzymes
Low Fat (1 Gram)

Creamy, Smooth, and Great Taste!

ST-5 with MigraStem’s FAB 5

FAB 5 BLENDS {BENEFITS}

1. MigraStem™ Whole Food Antioxidant
{Patent-pending MigraStem maximizes the use of 
your body’s own stem cells.†
 It contains potent whole food antioxidants, 
including goji fruit extract, organic fucoidan, 
organic GanoUltra™ mushrooms, maca, and 
fractionated colostrum— touting a host of health 
benefits widely known by Chinese herbalists.}

2. Triple Source Plant-Based Protein
{Triple source plant-based protein is 100% 
vegetarian and made with a combination of raw 
sprouted brown rice, pea and potato. It provides 
15 grams and 35% of the daily value, making it 
an excellent source of protein. Plus, it delivers a 
complete amino acid profile, helps with appetite 
suppression, and is easy to digest.† Gluten free 
and Non GMO.}

3. High Potency Vitamins and Minerals {Contains 
20 essential vitamins and minerals, providing 100% 
Daily Value of 16 key nutrients. Great liquid
alternative to taking a multivitamin in pill form.}

4. Fiber and Prebiotics
(Provides an excellent source of dietary fiber 
(10g), with 6.1 grams of soluble fiber. ST-5 
with MigraStem’s fiber and prebiotic blend 
supports a feeling of fullness, intestinal 
health, and immune health. †
 Contains Fibregum™ acacia gum, a proven 
prebiotic to help good bacteria thrive in the 
digestive tract.†}

5. Digestive Enzymes {A full spectrum of active, 
plant-sourced enzymes to help break down fats, 
carbohydrates and protein, aiding nutrient absorption.}


It’s not only what ST-5 with MigraStem contains, it’s also about what it doesn’t contain: No fillers, artificial flavors, gluten, soy, and genetically modified organisms.

INGREDIENTS / LABEL

ST-5™ with MigraStem™ feeds every cell with premium nutrition so your body can
run at its best. With 5 specialized blends comprised of stem cell nutrition and essential
nutrients, ST-5 with MigraStem helps optimize the migration of your body's own stem
cells into tissues in need of repair while supporting whole body wellness.† ST-5 with
MigraStem is packed with three sources of high quality plant-based protein, high fiber,
20 key vitamins and minerals, powerful antioxidants, exotic superfoods, prebiotics and
digestive enzymes — all in one delicious and nutritious scoop.
ST-5™ con MigraStem™ alimenta cada célula con nutrientes de alta calidad para que
su cuerpo pueda funcionar a su máximo potencial. Con 5 mezclas especializadas que
brindan nutrición para las células madre y nutrientes esenciales, ST-5 con MigraStem
ayuda a optimizar la migración de sus propias células madres a los tejidos en
necesidad de reparación y al mismo tiempo, apoya la salud y bienestar general.†
ST-5 con MigraStem está repleto de: 3 fuentes de proteína vegetal de alta calidad,
excelente contenido de fibra, 20 vitaminas y minerales esenciales, antioxidantes
poderosos, súperalimentos exóticos, prebióticos y enzimas digestivas — todo en una
deliciosa y nutritiva porción. Gluten Free / Soy Free / Non GMO
Sin Gluten / Libre de Soya / No OGM
REV1-JUL15 Item Code: 1954
Product of USA
Producto de EE.UU
WARNING: As with all dietary supplements, it is recommended that you consult your physician if you are pregnant or
nursing. Keep out of reach of children and pets. Do not use if safety seal is broken. Use as a dietary supplement only.
Not for weight reduction.
ADVERTENCIA: Como cualquier suplemento dietario se recomienda que consulte a su médico si está embarazada o

lactando. Mantener fuera del alcance de niños y mascotas. No lo utilice si el sello esta rasgado. Solo para ser utilizado como 

Supercharge Your Smoothie†
Potencie Su Batido†
DIETARY SUPPLEMENT / Net Wt 24.7 oz (700 g)
SUPLEMENTO DIETARIO / Peso Neto 24.7 oz (700 g)
Suggested Usage: 1 time daily.
Add 1 scoop to your smoothie, 8 oz of cold water or another healthy beverage. Mix well and enjoy. Best when consumed within 15 minutes of mixing.
Modo de Empleo: 1 vez al dia.
Añadir 1 cuchara medidora a su batido, 8 onzas de agua fría u otra bebida saludable. Mezclar bien y disfrutar. Se recomienda consumirlo en los
primeros 15 minutos de haberlo preparado.
Distributed by / Distribuido por:
Stemtech HealthSciences Corp.
Pembroke Pines, FL 33028
www.stemtech.com
1-888-Stemtech (783-6832)
Patents Pending / Patentes en Trámite
FIBERSOL® is a registered trademark of Matsutani Chemical Industry Co., Ltd.
FIBERSOL® es una marca registrada de Matsutani Chemical Industry Co., Ltd.
Fibregum™ is a trademark of Nexira
Fibregum™ es una marca registrada de Nexira
NutraFlora® is a registered trademark of GTC Nutrition Company
NutraFlora® es una marca registrada de GTC Nutrition Company
Ticaxin® is a registered trademark of Tic Gums, Inc.
Ticaxin® es una marca registrada de Tic Gums, Inc.
Store in a cool dry place. Conservar en lugar seco y fresco.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. †Estas declaraciones no han sido evaluadas por la Agencia de Alimentos y Medicamentos de Estados Unidos. Este producto no pretende diagnosticar, tratar, curar ni prevenir enfermedad alguna.
Other ingredients: Isomaltulose palatinose, natural vanilla flavor powder, Monk fruit extract (Siraitia grosvenorii), honey (granules). CONTAINS MILK (Fractionated Colostrum).
Otros ingredientes: Isomaltulosa palatinosa, sabor natural de vainilla, extracto de Luo han guo (Siraitia grosvenorii), miel (gránulos). CONTIENE LECHE (Calostro Fraccionado).
Supplement Facts / Datos del Suplemento
Serving Size / Tamaño de Porción 1 Scoop / 1 Cuchara Medidora (46.7g)
Servings Per Container / Porciones por Envase 15
Per Serving % Daily Value*
Calories 165 8%
 Calories from Fat 10 3%
Total Fat 1 g 1%
 Saturated Fat 0 g
 Trans Fat 0 g
Total Carbohydrates 24 g 8%
 Dietary Fiber 10 g 25%
 Soluble Fiber 6.1 g ‡
 Sugar < 1 g ‡
Protein 15 g 35%
Sodium 172.5 mg 7%
Vitamin A (Beta Carotene) 5000 IU 100%
Vitamin C (Acerola Cherry Fruit Extract) 60 mg 100%
Vitamin D3 (Cholecalciferol) 1000 IU 250%
Vitamin E (d-alpha Tocopheryl Acetate, Mixed Tocopherols) 22 IU 73%
Vitamin B1 (Thiamine Mononitrate) 1.5 mg 100%
Vitamin B2 (Riboflavin) 1.7 mg 100%
Niacin (Niacinamide) 20 mg 100%
Vitamin B6 (Pyridoxine HCI) 2 mg 122%
Vitamin B12 (Cyanocobalamin) 50 mcg 833%
Biotin 300 mcg 100%
Pantothenic Acid (Calcium D-Pantothenate) 10 mg 100%
Calcium (Dicalcium Phosphate) 1000 mg 100%
Phosphorus (Dicalcium Phosphate) 759 mg 76%
Iodine (Potassium Iodide) 150 mcg 100%
Magnesium (Magnesium Oxide, Magnesium Phosphate) 350 mg 87%
Zinc (Zinc Oxide) 15 mg 100%
Selenium (Selenium Yeast) 100 mcg 143%
Copper (Copper Gluconate) 0.5 mg 25%
Manganese (Manganese Sulfate) 2 mg 100%
Chromium (Chromium(III) Chloride) 120 mcg 100%
 Per Serving % Daily Value*
Triple Source Plant-Based Protein Blend 18.2 g ‡
 Pea Protein Isolate ‡
 Potato Protein Isolate ‡
 Brown Rice Sprouted Protein Isolate ‡
Fiber & Prebiotic Blend 10.4 g ‡
Soluble Dietary Fiber / Fibersol® 2 ‡
Acacia Gum / Fibregum™ ‡
Organic Xanthan Gum / Ticaxan® ‡
Fructooligosaccharides / NutraFlora™ ‡
MigraStem™ Whole Food Antioxidant Blend 950 mg ‡
Goji Juice Extract Powder (Lycium barbarum) ‡
GanoUltra™ Mushrooms (Ganoderma lucidum; Ganoderma applanatum) ‡
Fractionated Colostrum ‡
Fucoidan (Fucus vesiculosus) ‡
Maca PE (Lepidium meyenii) ‡
Digestive Enzyme Blend 250 mg ‡
 Bromelain ‡
 Protease ‡
 Cellulase ‡
 Hemicellulase ‡
 Invertase ‡
* Percent Daily Values are based on a 2,000 calorie diet. ‡ Daily Value not established.
Optimizes Stem Cell Migration and
Supports Whole Body Wellness†
Optimiza la Migración de Células Madre y Apoya
El Bienestar de Todo el Cuerpo †

Creamy Vanilla
Gluten Free / Soy Free / Non GMO

Sin Gluten / Libre de Soya / No OGM

FREQUENTLY ASKED QUESTIONS (FAQS) FOR YOUR INFORMATION
Can I use ST-5™ with MigraStem™ with SE3™, StemFlo® and StemSport®?
Yes. To obtain the maximum benefit, we suggest that StemFlo be taken one hour before
or one to two hours after you take ST-5 with MigraStem due to the protein in the mix.
However, as ST-5 with MigraStem is a liquid, it does pass through the stomach into the
intestine quickly, having little effect on the enzyme function in StemFlo.
How do I use ST-5 with MigraStem?
Mix it in any fluid of your choice. Blend with ice or frozen fruit. 

Can I make ST-5 with MigraStem into a hot drink?
You can make a warm beverage. The point is to not mix your ST-5 with MigraStem into
boiling liquid. Boiling liquid will destroy some of the nutrients. Simply heat your fluid and

mix in ST-5 with MigraStem. If the fluid does boil, let it cool before mixing in the product.

POTENTIAL USERS
• Everyone! No matter your age or activity level, you can benefit from ST-5 with
MigraStem.
• For people who want a high potency vitamin-mineral in one formulation without having
to buy multiple bottles.
• For anybody looking to even further optimize their daily renewal system.†
• For all who want to supplement their protein source with a high quality, low fat and NO
cholesterol plant-based protein.
• For all those desiring to assist in maintaining healthy body fat, muscle mass, and
strength.†
• For athletes who will want to make it a part of their daily supplement regime as it

provides complete high-quality absorbable protein and valuable essential nutrients

FOR YOUR INFORMATION

• Gluten free with no artificial coloring, artificial flavors, artificial
sweeteners, yeast or preservatives.
• ST-5 with MigraStem contains high quality non soy all vegetable/plantbased
protein blend that provides all nine of the essential amino acids;
the supplement is highly digestible and absorbable.
• Store in a cool dry location.
• If pregnant or nursing, consult with your healthcare practitioner.
• If one desires to consume the product in a weight loss program, then
use the product responsibly. It is not recommended that one consume
less that 1200 calories a day unless supervised by a healthcare
practitioner. It is advisable to consult a healthcare practitioner prior to
embarking on any weight loss regime.
• Protein has a tendency to satiate appetite, meaning making one
satisfied longer. For those interested in weight management, it
is recommended to eat a protein source first thing in a meal and
carbohydrates to follow. So push away the chips and bread, and reach
for a protein source first, such as ST-5 with MigraStem.
• For athletes: as protein is vital for muscle cell repair, it can be most
beneficial to drink ST-5 with MigraStem after exercise. For further
information on using ST-5 with MigraStem and the other Stemtech

products to support an active lifestyle,

KEY SCIENTIFIC FINDINGS

1. Fucoidan ingestion increases the expression of CXCR4 on
human CD34+ cells. Irhimeh MR, Fitton JH, Lowenthal RM. Exp
Hematol. 2007 Jun;35(6):989–94.
2. “A New Breakthrough in Stem Cell Nutrition ST-5™ with
MigraStem™”

by Christian Drapeau, July 2010

Discover The Power of Stem Cell Nutrition & Adult Stem Cells --

Discover The Power of Stem Cell Nutrition & 
Adult Stem Cells -- The Natural Renewal System of Your Body

I'm sure you've already heard about adult stem cells. Maybe you saw a news story, or a read an article. I'm also sure you've heard the terms pluripotent stem cells and embryonic stem cells. 

They have created a great deal of controversy and with good reason. The lure of what embryonic stem cells can do for the body has led to ethical issues surrounding such things as embryo harvesting. 

One thing remains, adult stem cells represent the future of health and wellness as we know it. And they're here to stay.


The Science Behind Stem Cell Nutrition.

Scientists discover that adult stem cells migrate from the bone marrow into the bloodstream, then into the tissues to renew and repair damaged and dead cells.


Studies now show that Adult Stem Cells have the same ability to become virtually any other cell in the body. That is, if a stem cell travels to the brain, it will become a brain cell, to a muscle, a muscle cell, to the liver, a liver cell and so on.



Scientists studying extracts from various natural botanical compounds such as Fucoidan (brown seaweed), and Aphanizomenon Flos Aquae (AFA), discover their ability to trigger a natural release in adult stem cells from the bone marrow.

"..Mesenchynal Stem Cells in the bone marrow give rise to the tissue stem cells, i.e. they have been shown to differentiate into bone and fat cells; tendons, ligament and other connective tissues, as well as neurons and cells of the liver, lung, pancreas and heart. That list is not exhaustive. Also, as their name implies Hematopoietic Stem Cells in the same bone marrow are the well known precursors to the wide variety of blood cells (red and white) and platelets."

Dr. Allan Somersall - The Amazing Power of Stem Cell Nutrition.



In short, the same benefits as embryonic stem cells can be achieved by enhancing the release of adult stem cells -- something your body is already doing and has been doing since the day you were born.

This research has led to the concept of stem cell nutrition, designed to promote the release of adult stem cells from the bone marrow, and their migration to the organs and tissues of the body that are in need of repair.
The Incredible Power of Adult Stem Cells At Work

1. 'Messengers' are sent by tissues in need, requesting the release of adult stem cells from the bone marrow.

2. Adult stem cells are realsed from the bone marrow and circulate in the bloodstream.

3. A different set of 'messengers' attract adult stem cells to migrate into tissues where the stem cells reproduce and become new healthy cells of that tissue.


4. The whole cycle of renewal continues for the duration of your life, 24 hour hours a day, 365 days a year, never stopping until you pass away.
Stem Cell Nutrition -- Your Future is Now

Stem cells occur naturally in the body and serve to replenish cells that are lost through normal wear and tear or injury. 

As we age, our body's ability to self-repair and maintain optimum health decreases due to a reduction in the number of circulating stem cells associated with the normal aging process. 

Increasing the number of circulating stem cells is believed to support the body's process of self-repair and self-renewal.

Our bodies have to maintain a fine balance between breakdown and renewal. The cells of your body are constantly being damaged and replaced and this process is accelerated by stress, pollution and other lifestyle choices.

Stem Cell Science represents a new paradigm in anti-aging and the quest to maintain optimal health.

Stem Cell Science Experts Agree

"The lack of success of embryonic stem cells should be compared with the real successes of adult stem cells. A wealth of scientific papers published over the last few years document that adult stem cells are a much more promising source of stem cells for regenerative medicine." 

- Dr. David A. Prentice, Ph.D.

Stem Cell Nutrition Proven Clinical Studies

Mobilization of human stem cells study published in the Journal of Cardiovascular Revascularization Medicine. (Click for PDF

Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells. Published in the Journal of Experimental Hematology.

Stem Cell Nutrition Frequently Asked Questions

Here are some of the most common answers to questions about Stem Cell Nutriton.


Where can you order Stem Cell Nutrition?

Whilst blue-green algae and spirulina have been popular for more than 40 years, the idea to extract and use the compunds that trigger stem cell release is relatively new. The #1 stem cell nutrition product is StemEnhance Ultra. It comes with a 30 day money back guarantee and is available to order online.

What is Stem Cell Nutrition?

Stem Cell Nutrition is a new concept in the health and wellness field, where extracts from various natural botanical compounds trigger a release of bone marrow stem cells into the blood stream. These stem cells then travel around the body where they are signaled by tissues to become healthy new cells.

What are the side effects of Stem Cell Nutrition?

There are no known side effects. StemEnhance Ultra contains the same amount of Vitamin K as a serve of brocolli, and some people on blood thinning medication need to be aware of their vitamin K intake. You may however feel more alert, have increased mental clarity, and have better moods as a result of the 12 to 16 mg of naturally occuring PEA found in StemEnhance Ultra. People have also reported a reduction in aches and pains and a better overall sense of well-being. The body seems to respond well to having bone marrow stem cells released into the bloodstream.

What is 'The Amazing Power of Stem Cell Nutrition?

The Amazing Power of Stem Cell Nutrition is a book written by the late Dr Allan Somersall. Dr Somersall was a great supporter of stem cell research, a vibrant and energetic presenter, and he came up with the phrase, 'Everybody has stem cells; everybody uses stem cells; everybody uses stem cells everyday; stem cells work..and they work every time.' He work lives on at stemcellnutrition.com

Which countries is Stem Cell Nutrition available?

At this stage, StemEnhance is available in the US, Canada, Australia, New Zealand, France and Martinique. It will be available in many more countries as we undertake the product registration process.

What are the major Stem Cell Nutrition companies?

The pioneer in stem cell nutrition was Desert Lake Technologies, now known as Cerule, who developed StemEnhance and licensed it to other companies including StemTech. StemTech has recently filed for chapter 11 Bankruptcy and Cerule is set to become the leader in the market, with unfetted access to the Lake Klamath algae supply.

Isn't the algae used in Stem Cell Nutrition toxic?

Not at all. Whilst the whole AFA and microcystin are often found together, Cerule has invested into state of the art harvesting and filtration facilities. They hold many patents and the centrifugal filtering process takes up an entire room. The algae is tested many times will not contain any more than 1 million parts per million of mycrocystin as per the standard set by the State of Oregon.

Is Stem Cell Nutrition available for Dogs and Horses?

There are no specific products for dogs and horses at this stage, but they can consume regular StemEnhance Ultra if mixed with their food. As mammals, they have the same bone marrow system and experience the same results.


Monday, February 13, 2017

What Are Stem Cells?

What Are Stem Cells?

Stem cells are unique cells of the body in that they are unspecialized and have the ability to develop into several different types of cells. They are different from specialized cells, such as heart or blood cells, in that they can replicate many times, for long periods of time. This ability is what is known as proliferation. Unlike other cells, stem cells also have the ability to differentiate or develop into specialized cells for specific organs or to develop into 
tissues. 
In some tissues, such as muscle or brain tissue, stem cells can even regenerate to aid in the replacement of damaged cells. Stem cell research attempts to take advantage of the renewal properties of stem cells by utilizing them to generate cells for tissue repair and the treatment of disease.

Where Are Stem Cells Found?

Stem cells come from several sources in the body. The names of the cells below indicate the sources from which they are derived.

Embryonic Stem Cells
These stem cells come from embryos in the early stages of development. They have the ability to differentiate into any type of cell in the initial stages of development and become slightly more specialized as they mature.

Fetal Stem Cells
These stem cells come from a fetus. At about nine weeks, a maturing embryo enters into the fetal stage of development. Fetal stem cells are found in fetal tissues, blood and bone marrow. They have the potential to develop into almost any type of cell.

Umbilical Cord Blood Stem Cells
These stem cells are derived from umbilical cord blood. Umbilical cord stem cells are similar to those found in mature or adult stem cells. They are specialized cells that develop into specific types of cells.

Placental Stem Cells
These stem cells are contained within the placenta. Like cord blood stem cells, these cells are specialized cells that develop into specific types of cells. Placentas however, contain several times more stem cells than do umbilical cords.

Adult Stem Cells

These stem cells are present in mature body tissues in infants, children and adults. They may also be found in fetal and umbilical cord blood cells. Adult stem cells are specific to a particular tissue or organ and produce the cells within that particular tissue or organ. These stem cells help to maintain and repair organs and tissues throughout a person's life.

Types of Stem Cells

Stem cells can be categorized into five types based on their ability to differentiate or their potency. The stem cell types are as follows:

Totipotent Stem Cells

These stem cells have the ability to differentiate into any type of cell in the body. Totipotent stem cells develop during sexual reproduction when male and female gametes fuse during fertilization to form a zygote. The zygote is totipotent because its cells can become any type of cell and they have limitless replicative abilities. As the zygote continues to divide and mature, its cells develop into more specialized cells called pluripotent stem cells.

Pluripotent Stem Cells
These stem cells have the ability to differentiate into several different types of cells. Specialization in pluripotent stem cells is minimal and therefore they can develop into almost any type of cell. Embryonic stem cells and fetal stem cells are two types of pluripotent cells.

- Induced pluripotent stem cells (iPS cells) are genetically altered adult stem cells that are induced or prompted in a laboratory to take on the characteristics of embryonic stem cells. Although iPS cells behave like and express some of the same genes that are expressed normally in embryonic stem cells, they are not exact duplicates of embryonic stem cells.

Multipotent Stem Cells
These stem cells have the ability to differentiate into a limited number of specialized cell types. Multipotent stem cells typically develop into any cell of a particular group or type. For example, bone marrow stem cells can produce any type of blood cell. However, bone marrow cells don't produce heart cells. Adult stem cells and umbilical cord stem cells are examples of multipotent cells.

- Mesenchymal stem cells are multipotent cells of bone marrow that have the ability to differentiate into several types of specialized cells related to, but not including blood cells. These stem cells give rise to cells that form specialized connective tissues, as well as cells that support the formation of blood.

Oligopotent Stem Cells
These stem cells have the ability to differentiate into just a few types of cells. A lymphoid stem cell is an example of a oligopotent stem cell. This type of stem cell can not develop into any type of blood cell as bone marrow stem cells can. They only give rise to blood cells of the lymphatic system, such as T cells.

Unipotent Stem Cells
These stem cells have unlimited reproductive capabilities, but can only differentiate into a single type of cell or tissue. Unipotent stem cells are derived from multipotent stem cells and formed in adult tissue. Skin cells are one of the most prolific examples of unipotent stem cells. These cells must readily undergo cell division to replace damaged cells.


Sources:
Stem Cell Basics: Introduction. In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2002. Available at (http://stemcells.nih.gov/info/basics/pages/basics1.aspx)

Image: Nissim Benvenisty / Russo E (2005) Follow the Money—The Politics of Embryonic Stem Cell Research. PLoS Biol 3(7): e234. doi:10.1371/journal.pbio.0030234

Friday, November 18, 2016

Steps To Getting Started In Jeunesse


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Steps To Getting Started In Jeunesse

1.Jeunesse Distributor Signup. Click Here To Join Now. 

Click Here And Watch This Youtube 'Signup Tutorial Video.' 

Welcome to Generation Young,
One Team One Family One Jeunesse !

Soong See Choo
Independent Jeunesse Global Distributor Sponsor ID : soongworld


Luminesce (Personal Care)

The series is a component of Y.E.S (Youth Enhancement System), LUMINESCE™ super-charges the production of young, fresh skin cells. New cell growth is an essential part of life. The production of new cells decelerates as we age, and at the same time, our cells age and functions begin to slow. Aging skin cells can cause our skin to be dull, having a sagging complexion, and the cells’ efficiency to accept nutrients and to remove toxins are reduced.

Click To Watch Youtube Video Dr Nathan Newman Stem Cell Technology by JEUNESSE®

Dr. Nathan Newman, a world-renowned dermatologist and cosmetic surgeon, began searching for a topical treatment to help patients recovering from burns and severe injuries. Knowing that stem cells drive cell growth and regeneration, he isolated the stem cell growth factors that serve as the “language” communicating cellular activity. Although other scientists were using plant-based growth factors, Dr. Newman derived his growth factors from the stem cells of healthy adults, theorizing that cell communication in the same “language” would be more effective. The results were remarkable. And his 200+ growth factor complex is what you’ll experience in LUMINESCE™ products from Jeunesse. This potent growth factor complex is able to rejuvenate skin cells faster and at a molecular level. New cell production is stimulated, resulting in increased collagen and elastin for firmer skin tone. New cells also give your complexion a fuller appearance with a healthy, vibrant glow. With LUMINESCE™, skin appears younger, because at the cellular level, it literally is younger.

Click To Watch Youtube Video Dr Nathan Newman Explains Concept Behind Jeunesse® Global LUMINESCE™


The Jeunesse Luminesce series comprises of the Cellular Rejuvenation Serum (main flagship product), Daily Moisturizing Complex, Advanced Night Repair, Essential Body Renewal, Youth Restoring Cleanser, Ultimate Lifting Masque. Infused with a potent growth factor complex derived from natural adult stem cells, the LUMINESCE™ family of products rejuvenates skin cells at a molecular level.
A Quick Illustration of How The Technology Works
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Main LUMINESCE Series
LUMINESCE™ Cellular Rejuvenation Serum
This silky serum has the highest percentage of growth factor complex possible to encourage cell renewal. Use it twice daily after cleansing and as a primer for the daily moisturizing complex or advanced night repair. Its corrective properties make this the most popular product in the LUMINESCE line.
Benefits
  • Helps even out discolored and blotchy skin tones
  • Provides a youthful luminosity to the skin
  • Minimizes the appearance of fine lines and wrinkles
  • Refreshes collagen and elastin
  • Helps maintain smooth skin texture
  • Replenishes skin’s natural stores of proteins to sustain a youthful, firm appearance
  • All natural, hypoallergenic, and paraben free
LUMINESCE™ Daily Moisturizing Complex
A brilliant, all-day facial cream with serious skin-defending properties. The daily moisturizing complex contains apple, lentil, and watermelon extracts to lock in hydration, while green algae extract naturally protects against the sun’s rays. The patent-pending LUMINESCE™ growth factor complex revives cells which contribute to that age-defying glow.
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Benefits
  • Immediately hydrates skin while delivering 24-hour protection
  • Increases intracellular hydration by 85% in two weeks, and can reduce the appearance of fine lines in as little as two hours*
  • Red seaweed extract provides a natural barrier to keep in moisture†
  • Green algae extract supplies natural UVA/UVB protection††
  • Packed with essential vitamins, including a rich supply of vitamin C that diminishes the appearance of age spots and evens skin tone
  • Paraben and oil free
LUMINESCE™ Advanced Night Repair
A rich cream that corrects environmental damage while you sleep, advanced night repair propels your skin into a cycle of self-restoration while fortifying it for the future. Powerful vitamins and antioxidants protect cell membranes from free radical damage. This formula works its hardest at night—when cellular renewal is most active.
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Benefits
  • Increases intracellular hydration by 85% in just two weeks
  • Reduces the appearance of fine lines and wrinkles in as little as two hours†
  • Protects against free radical damage† with the LUMINESCE™ skin vitamin complex
  • Stem cell growth factors restore luminosity and firmness in the skin
  • Diminishes the appearance of age spots and evens skin tone
  • Increases skin firmness and elasticity
LUMINESCE™ Essential Body Renewal
Indulge in the restorative powers of LUMINESCE™ all over. This feather-light body lotion delivers the ultimate in hydration and cellular rejuvenation. Essential body renewal gently nourishes and softens all skin types—particularly in rough, dry areas. Repair the effects of environmental damage while protecting against premature aging.
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Benefits
  • Naturally restores by hydrating and smoothing skin
  • Boosts skin elasticity and locks in moisture
  • Protects against free radicals and other environmental damage
  • Evens skin tone and helps combat photoaging
  • Contains anti-inflammatory properties
  • Helps delay signs of aging with antioxidants that neutralize free radical damage
  • Visibly repairs dry, damaged skin and soothes itchy or irritated areas
LUMINESCE™ Youth Restoring Cleanser 
Restore your skin’s natural brilliance by detoxifying deep within the cells. As the first step in the LUMINESCE™ skincare system, this cleanser conditions and purifies at microscopic levels. Ingredients are carefully formulated to maintain the nutrients and moisture needed to support cell renewal.
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Benefits
  • Studies show smoother, brighter, and younger looking skin
  • Helps reduce acne, blemishes, and other skin impurities
  • Increases the effectiveness of the LUMINESCE™ skincare system
  • Gently exfoliates and removes toxins on a cellular level without over-drying your skin
  • Helps protect and nourish your skin
  • Delays signs of aging
  • Lightweight formula won’t leave waxy or oily residue
LUMINESCE™ Ultimate Lifting Masque
LUMINESCE™ ultimate lifting masque combines the natural powers of tara and chicory root to instantly lift and hydrate skin. Designed to reduce the appearance of fine lines and wrinkles, this masque is bolstered by a patent-pending stem cell technology exclusive only to Jeunesse.
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Benefits
  • Instantaneously lifts while providing long-term hydration
  • Deeply nourishes to produce supple skin
  • Contains special blends of vitamins and antioxidants
  • Effectively diminishes the appearance of aging
  • Bolsters the performance of the LUMINESCE™ skincare system
  • Contains cucumber extract to soften skin
  • Gently expels contaminants like blackheads and blemishes caused by bacteria
  • Tightens and firms skin

To Watch Youtube Video Click Here Stem Cell Presentation for Jeunesse® LUMINESCE™ with Dr Nathan Newman


Click Here To Watch Video Dr Nathan Newman Traditional Stem Cell Face Lift on Entertainment Tonight



F.A.Qs
What is the advantage of the adult stem cell technology in LUMINESCE™ cellular rejuvenation serum?
The adult stem cell conditioned media in LUMINESCE™ cellular rejuvenation serum contains cytokines, which have the same attributes as the cytokines in the human body. This allows for a perfect interaction between our product and natural skin cell processes. The growth factors and cytokines provided by the stem cell technology work with the natural processes of the skin to support rejuvenation and decrease the appearance of fine lines and wrinkles.
Does LUMINESCE™ cellular rejuvenation serum contain live stem cells?
There are no stem cells in the serum. A natural liquid media is conditioned by the human adult stem cells. This conditioned media now full of over 200 growth factors is completely separated and this is what is used in LUMINESCE Cellular rejuvenation serum.
LUMINESCE™ cellular rejuvenation serum contains more than 200 growth factors. How many growth factors are normally in such a prestigious product?
There is no product currently on the market that rivals LUMINESCE™ cellular rejuvenation serum. Although a few products claim to use stem cell’s, they are generally derived from plants and fruits such as apples. Since we are humans and not plants these plant stem cells cannot communicate with our cells like human-derived growth factors do.
What is the timeframe to see these visible results?
As the effects of LUMINESCE™ cellular rejuvenation serum work in tandem with natural processes of skin renewal, visible results will vary from person to person due to varying skin types. Moderate skin renewal may occur within four weeks, but optimal improvement to the skin is generally not reached until after three months of daily use.
What is the best way to apply LUMINESCE™ cellular rejuvenation serum?
LUMINESCE™ cellular rejuvenation serum comes in a pre-measured pump. One to two pumps of the serum applied to the face and neck morning and evening, is the recommended usage. After washing your face, you may choose to apply a toner first. However, no other creams or serums should be applied before LUMINESCE™ cellular rejuvenation serum as this could block the product from being properly absorbed into the skin.