Pain-relieving drugs such as aspirin and products containing acetaminophen - many are toxic to human liver.
Most pharmaceutical drugs, especially anti-inflammatories and antibiotics - check the Physician's Desk Reference (PDR), available in a home edition and at most public libraries, if you are uncertain about the potential toxicity to the human liver.
Fried greasy foods - they are often difficult for the liver to handle.
Stimulants like coffee, black tea, or ephedra (ma huang) products - they increase body metabolism and acts as central nervous system stimulants, increasing body heat and possibly inflammation. Inflammation overtime, cause cancerous cells in the body.
A normal human body's liver physiology function, in a nutshell, is to make sure that the body absorbs everything it needs and dumps everything it doesn't need.
Liver's major duties look like this :
1.Metabolizes(change) proteins, fats, and carbohydrates, thus providing energy and nutrients.
2.Stores fuel in the form of glycogen, which is especially important to your brain function, and can supply "quick energy".
3.Metabolizes drugs and breaks down alcohol. All patients with liver diseases( hepatitis, cirrhosis, fibrosis) must avoid alcohol.
4.Stores vitamins, minerals, and sugar.
5.Filters the blood and helps remove harmful chemicals and bacteria. Without sufficient water on daily basis this normal function is hindered.
6.Creates bile, which breaks down fats. Again dehydration can shut down bile production, and lead to gall bladder stones formation.
7.Regulates the body's ability to clot.
8.Governs the transport of fat stores.
9.Helps assimilate and store fat-soluble vitamins (A,D,E,K); stores iron.
10.Stores extra blood, which can be quickly released when needed.
11.Creates serum proteins, which maintain fluid balance and act as carriers for hormones like estrogen and other substances.
12.Helps maintain electrolyte and water balance.
13.Creates immune substances, such as gamma globulin.
14.Regulates levels of sexual hormones: manufactures estrogen, testosterone, and breaks down and eliminates excess sexual hormones.
As you can see, that's a lot of work for a single organ to do even under the best of conditions. Please don't insult your body further by short-changing it without enough water daily. Why should one die prematurely and intentionally?