How does aspirin work?

Warning: If you have been taking aspirin, do not read on. If you ignore this warning, then be ready to change your approach to your own health, henceforth.

Aspirin is normally sold as 300mg tablets and can safely be taken at a rate of two or three tablets every four to six hours , to a maximum dose of a dozen tablets or about 4 gram per day. Hope the user/care giver keeps track of the amount every day.

A single dose of 10 g (30 tablets) is life-threatening for an adult because it makes the human blood too acidic. The body tries to cope by rapid breathing to dispel CO2 (carbon dioxide) and thereby reduce acidity, and by boosting the action of the kidneys, which leads to dehydration. If the acidity cannot be corrected (by drinking more water gradually) by natural means, tissue damage occurs and eventually death.

How does aspirin work?

Aspirin interferes with an enzyme that makes prostaglandins. We need these chemicals to regulate digestion, kidney function, blood circulation and reproduction.

Prostaglandins also generate pain signals, when cells are dehydrating before thirst signal is activated. Hence, we cannot use thirst as the gage to drink the next round of water. Drink your own 10% of water quota daily, every 90 minutes to keep regular and constant re-hydration for the cells. And use 1/4 teaspoon of sea-salt for every 1250 ml water drank, in your daily diet. Avoid all table-salt. Your own water quota is calculated by 31.42 x (you own body weight in kilogram). One kilogrm is about 2.2 pounds.

Prostaglandins are releases in many injuries and disease, and it is because of them that we suffer inflammation, pain and fever. Now if we truly understand the body wisdom to have these symptoms then we can appreciate it defense and immunity systems at work for its own survival. Inflammation is the concentration of "worker-cells" repairing the injured area; pain is the signal calling for more constant water intake to facilitate the intensive repair work going on ; fever is to enable the white blood cells 'fight' better at slightly higher temperature than normal body temperature.

There is a whole sequence of bio-chemical reactions which lead to the appearance of prostaglandins, and the first is the liberation of the polyunsaturated fatty acid called arachidonic acid from a cell membrane. This acid reacts with oxygen to form chemicals such as cyclic prostaglandin endoperoxides that trigger inflammation. When the intensive repair work is completed, the inflammation will subside naturally. Aspirin / anti-inflammation drug blocks the enzyme which controls this reaction and so prevents the chain of rescue events which starts with a broken cell membrane (water content is lost, dehydration happening very fast) and leads to painful prostaglandins being produced.

Doctors, please don't fight the body natural way to survive with more drugs. Help the victims understand what is going on in the body. Remember, the doctor's code is to help and facilitate recovery and healing to the body, not haphazardly endanger it further. Steroids like cortisone, morphine and NSAIDs (non-steroid anti-inflammatory drugs) cannot do the job naturally.